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  • 1
    Electronic Resource
    Electronic Resource
    Identification of iron sulphide grains in protoplanetary disks (2002)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 417 (2002), S. 148-150 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sulphur is depleted in cold dense molecular clouds with embedded young stellar objects, indicating that most of it probably resides in solid grains. Iron sulphide grains are the main sulphur species in cometary dust particles, but there has been no direct evidence for FeS in astronomical ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/417148a
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  • 2
    Electronic Resource
    Electronic Resource
    Infrared data of sulphides of interstellar dust importance
    Amsterdam : Elsevier
    Infrared Physics and Technology 35 (1994), S. 361-374 
    Details
    ISSN: 1350-4495
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/1350-4495(94)90094-9
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  • 3
    Electronic Resource
    Electronic Resource
    NIR high-resolution imaging of young stars
    Amsterdam : Elsevier
    Infrared Physics and Technology 35 (1994), S. 487-491 
    Details
    ISSN: 1350-4495
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/1350-4495(94)90105-8
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  • 4
    Electronic Resource
    Electronic Resource
    Judicial Summation: The Trial Judge's Version of the Facts or the Chimera of Neutrality (1999)
    Springer
    International journal for the semiotics of law 12 (1999), S. 169-210 
    Details
    ISSN: 1572-8722
    Source: Springer Online Journal Archives 1860-2000
    Topics: Law
    Notes: Abstract This paper analyses some of the rhetorical and linguistic features of two judges' summations to two different juries in a criminal case that was tried twice in the Tasmanian Criminal Court. In the first trial, the jury failed to reach a verdict upon a number of counts in the indictment. In the second trial, the jury returned guilty verdicts on all counts. The purpose of this paper is to cast light upon how the linguistic and rhetorical features observed in the summations lent colour or weight to a particular interpretation of the events tried. The paper argues that the judge's summing up is part of the persuasive process of the criminal trial and that judges do present a version of the facts to the jury, deploying various language strategies to construct and communicate that version. The analysis focuses solely upon the judges' summing up of the evidence and the facts. It does not deal with directions or determinations concerning the law. Three major differences between the summations are considered: their distinct thematic approaches to the factual issues, the disparate levels of assistance they provide to the jury in assessing the evidence and their relative comprehensibility. The different thematic approaches produced disparate choices concerning the evidence -- its selection for consideration and its evaluation. The approach in the first summation resulted in an analysis of the evidence that favoured the accused. In the second summation, the thematic approach facilitated a more critical appraisal of the accused's case and a more favourable assessment of the complainant's version of events. The summations also provide differential levels of assistance and achieve differential levels of comprehensibility. The first summation provides relatively little guidance to the jury in evaluating significant items of evidence. In contrast, the second trial summation gives a more directional appraisal. It also achieves a greater level of clarity in the communication of key ideas than the first summation. Both distinctions are attributed to the discourse structures of the summations and to the second summation's reliance upon such organisational and rhetorical devices as repetition, enumeration and rhetorical questions. They are also attributed in part to the comparative syntactic simplicity of the second summation's sentences. It is the conclusion of this paper that the trial judge's linguistic, discourse construction and rhetorical skills are central to the clarification or obfuscation of the facts and issues in a case. How judges say what they say is significant at two levels of sense construction -- at the level of what Bernard Jackson calls “signification” and at the level of communication.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008942707893
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  • 5
    Electronic Resource
    Electronic Resource
    ISO's View on AFGL 4106 (1997)
    Springer
    Astrophysics and space science 255 (1997), S. 469-475 
    Details
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1001574510845
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  • 6
    Electronic Resource
    Electronic Resource
    The nature of the 10 and 20 micrometer features in circumstellar dust shells (1983)
    Springer
    Astrophysics and space science 97 (1983), S. 405-419 
    Details
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract In this paper we study the influence of model parameters adopted in radiative transfer computations on the shape of the 10 and 20 μm bands observed in IR spectra of Becklin-Neugebauer objects and O-rich giants and supergiants. The calculations show that besides the wavelength-dependence of the absorption efficiency the optical depth is the most important parameter. From the appearance of the 10 μm feature we can distinguish three different regions: emission, self-absorption and absorption. The most important effect demonstrated by the model computations is that an emission feature shows a weaker variation than an absorption feature if the optical depth is increased or decreased. Furthermore shells with central-peaked density distributions should exhibit stronger emission bands and weaker absorption bands than shells with a constant density.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00653496
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  • 7
    Electronic Resource
    Electronic Resource
    Observationally-based infrared efficiencies and planck means for circumstellar dust grains (1983)
    Springer
    Astrophysics and space science 94 (1983), S. 333-349 
    Details
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract In this paper the mean relative efficiency factors for absorption of dust grains in the wavelength range from 8 to 22 μm have been derived from IR spectra of the optically thin dust shells surrounding the O-rich supergiants μ Cep, αOri, X Her, and R Cas. The resulting absorption efficiency curve has been extrapolated into the near as well as the far infrared regions, having regard to restrictions set by experience. Planck mean efficiency factors have been calculated for the temperature range from 30 to 1500 K. The curveQ P(T), which shows a maximum atT=300 K, has been approximated conveniently by a power law on either side of this maximum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00653723
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  • 8
    Electronic Resource
    Electronic Resource
    The cardioprotector ADR-529 and high-dose epirubicin given in combination with cyclophosphamide, 5-fluorouracil, and tamoxifen: a phase I study in metastatic breast cancer (1994)
    Springer
    Cancer chemotherapy and pharmacology 34 (1994), S. 439-443 
    Details
    ISSN: 1432-0843
    Keywords: Key words: ADR-529 – Cardioprotection – Metastatic breast cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The purpose of this study was to determine the maximal tolerable dose (MTD) of epirubicin and ADR-529 given in combination with cyclophosphamide, 5-fluorouracil, and tamoxifen. A total of 64 breast cancer patients with locally advanced disease or a first metastatic event were included. Using fixed doses of cyclophosphamide, 5-fluorouracil, and tamoxifen, cohorts of ten patients were treated with escalating doses of epirubicin and ADR-529. With the use of protocol criteria specifying evaluation after the first course, the MTD was not reached. Dose reductions carried out due to hematologic toxicity during the first four courses made it impossible to escalate doses of epirubicin beyond 80 mg/m2 given together with ADR-529 600 mg/m2. The vascular toxicity of ADR-529 necessitated central venous access in a number of patients. For phase III evaluation of ADR-529 given together with cyclophosphamide, epirubicin, 5-fluorouracil, and tamoxifen (CEF/TAM) we recommend using epirubicin/ADR-529 at 60/600 mg/m2. Together with evaluation of the cardioprotective properties of ADR-529, we recommend evaluating the impact of ADR-529 on the efficacy of cytotoxic therapy and investigating further the toxicity of ADR-529.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00685571
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  • 9
    Electronic Resource
    Electronic Resource
    Multiple-dose pharmacokinetics of epirubicin at four different dose levels: studies in patients with metastatic breast cancer (1991)
    Springer
    Cancer chemotherapy and pharmacology 28 (1991), S. 63-68 
    Details
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Pharmacokinetic analysis of epirubicin and its metabolites epirubicinol and 7-deoxy-13-dihydro-epirubicinol aglycone during the first and the fourth courses of treatment was performed in 78 patients with metastatic breast cancer. The patients were treated every 3 weeks with epirubicin given as 10-min i.v. infusions at four different dose levels: 40, 60, 90 and 135 mg/m2. In most cases (76 of 78 cases), plasma concentration-time curves fitted to a three-compartmental pharmacokinetic model. The terminal half-life of epirubicin was independent of dose and duration of treatment. Large interindividual differences were demonstrated (meant 1/2γ, 21.6±7.9 h; range, 10.6–69 h;n=110). In two subjects, extremely long half-lives and high serum bilirubin concentrations indicated impaired liver function. No correlation was found between the half-life and levels of liver alanine aminotransferase (ALAT) or serum creatinine. The metabolite epirubicinol appeared quickly after epirubicin administration and its half-lives were shorter than that of the parent compound (meant 1/2γ, 18.1±4.8 h; range, 8.2–38.4 h;n=105).Formation of the aglycone metabolite was delayed and the half-life of this metabolite was shorter than that of epirubicin (meant 1/2γ, 13±4.6 h; range, 2.7–29 h;n=104). The AUC of epirubicin and the total AUC (drug and metabolites) were linearly proportional to the dose, with the former value constituting two-thirds of the latter. A correlation was found between AUC and the plasma concentration of epirubicin at two time points (2 and 24 h after administration). The proposed model was AUC=9.44×c 2+62.5×c 24+157.7 (r=0.953).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00684959
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  • 10
    Electronic Resource
    Electronic Resource
    A randomized study of epirubicin at four different dose levels in advanced breast cancer. Feasibility of myelotoxicity prediction through single blood-sample measurement (1991)
    Springer
    Cancer chemotherapy and pharmacology 28 (1991), S. 465-469 
    Details
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Detailed pharmacokinetic analysis and subsequent evaluation of myelotoxicity were performed in 55 patients who had been randomized to 4 different doses of epirubicin (40, 60, 90 or 135 mg/m2 given i.v. every 3 weeks). A significantly positive correlation was demonstrated between the AUC and the myelotoxicity of epirubicin. A similar correlation was observed when the metabolite epirubicinol was also considered. The decrease in leucocyte count as expressed by the logarithmic ratio between nadir WBC and initial WBC was linearly correlated with the AUC of either epirubicin alone (r=−0.55,P〈0.001) or epirubicin and epirubicinol together (r=−0.63,P〈0.001). As a relationship between the concentration of epirubicin in a single plasma sample taken at 6 h following i.v. administration and the AUC of the drug has been established, a log-linear relationship between the expected decrease in leucocytes and the concentration at 6 h after administration could be calculated. The proposed model is expressed as the equation: log WBCnadir=log WBCinitial−0.0073×c 6 (ng/ml) −0.14.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00685824
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