Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The inducible nitrogen oxygen synthase (iNOS) and nitric oxide (NO) system acting in concert with superoxide radicals is recognized as a powerful macrophage microbicidal mechanism. However, experimentation with iNOS knockout mice has rendered contradictory results on the protective role of iNOS/NO in the course of mycobacterial infections. On the other hand, NO also plays an immunoregulatory role. Knowing the nature of the mycobacterial constituents that induce iNOS gene expression would help to better understand the host–parasite relationship.Lipoarabinomannan (LAM) and a 19 KDa lipoprotein are the two known mycobacterial constituents that have shown to induce iNOS. By screening a set of methanol extracted lipids from Mycobacterium microti, here we provide evidence that multiple mycobacterial molecules of lipidic nature both of intermediate and of high polarity, with free amino groups or carbohydrates but no phosphate groups as part of their structure are capable of inducing iNOS gene expression in J774 cells, thus implying a complex relationship between mycobacteria and their host immune system in regard to iNOS gene expression.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 33 (2000), S. 938-946 
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: The problem of removing the characteristic parasitic errors of the high-accuracy universal polarimeter method in a linearly birefringent and optically active crystal section is examined. The use of constant parasitic errors typical of each particular polarimetric system is shown to be inappropriate. The parasitics should preferably be determined in each measurement process, since the instrumental parasitics depend not only on the optical and mechanical elements of the experimental system (polarizers, rotators, detection unit etc.), but on sample quality, alignment of the system, and even in many cases on exactly where the light beam passes through the sample. Thus, measurements with different samples give different values of parasitic errors. Such instrumental parasitics can be held within the same order of magnitude for different samples (∼10−4) if they are of good optical quality. However, the parasitics are increased by an order of magnitude (∼10−3) when the samples are of moderate or bad optical quality. Optical anisotropy properties as coefficients of thermal variation of the birefringence of KDC and KDP single crystals and the optical activity of KDP at 632.8 nm wavelength are obtained, in the ranges from room temperature to 353 K and to 373 K, respectively.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 480-481 (Mar. 2005), p. 43-52 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The complete optical gyration tensor of monoclinic pure L-arginine phosphatemonohydrate (LAP) and deuterated LAP (d-LAP) crystals has been determined. Variation of the optical activity in the presence of birefringence of d-LAP crystal with pure LAP is found from the high-accuracy universal polarimeter (HAUP) method at a wavelength of 632.8 nm. The gyration tensor components in terms of rotatory power were found to be r11 = -6.6(3) º/mm, r22 = 19(2)º/mm; r33 = 49.7(7) º/mm; and r13 = -43.7(8) º/mm for the LAP, and r11 = -1.2(1) º/mm, r22 = 5.0(4) º/mm; r33 = 41.4(3) º/mm; and r13 = -38.0(4) º/mm for d-LAP at room temperature
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...