ISSN:
0030-4921
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The positions of conformational equilibria in 1,5-, 1-6- and 1,8-dimethylperhydro-oxazolo[3,4-a]pyridines were determined by 1H NMR spectroscopy. The cis-(H-5, H-8a)-1,6-dimethyl-perhydro-oxazolo[3,4-a]pyridine. In contrast, r-1,t-6,t-8a-1,6-dimethylperhydro-oxazolo[3,4- a]pyridine preferred the cis-fused conformation. Three of the 1,8-dimethylperhydro-oxazolo[3,4-a]pyridines adopted the trans-fused conformations (with distortion of the system in the case of the r-1,c-8,c-8a derivative) and the r-1,c-8,t-8a-1,8-dimethyl derivative adopted the cis-fused conformation.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1270200411
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