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  • 1
    Electronic Resource
    Electronic Resource
    Book reviews (1982)
    Springer
    Origins of life and evolution of the biospheres 12 (1982), S. 119-121 
    Details
    ISSN: 1573-0875
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00926916
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Editorial (1985)
    Springer
    Origins of life and evolution of the biospheres 15 (1985), S. 219-219 
    Details
    ISSN: 1573-0875
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01808169
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Studies on Order in Prebiological Systems at the Laboratory of Chemical Evolution (1998)
    Springer
    Origins of life and evolution of the biospheres 28 (1998), S. 123-130 
    Details
    ISSN: 1573-0875
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Notes: Abstract The basic tenet of investigations in the Laboratory of Chemical Evolution (LCE) under Cyril Ponnamperuma was that biology is a recapitulation of prebiology, and that protobiology is an outcome of simple molecular interactions, engendered by the physics and chemistry of the molecules themselves. Studies were undertaken to continue research into understanding the determining physical and chemical parameters of molecular interactions leading to increasing complexity in pre- and proto-biological systems. Among other, related work, research was performed on the origin of the genetic code, the origin of order in prebiotic polymers, and related studies on the origins of optical activity in biological macromolecules. Highlights of some these studies are presented here.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006520106159
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    pH Dependence of 2,3-diphosphoglycerate binding to human hemoglobin Ao at 21.5°C (1986)
    New York, NY : Wiley-Blackwell
    Proteins: Structure, Function, and Genetics 1 (1986), S. 164-175 
    Details
    ISSN: 0887-3585
    Keywords: DPG ; organophosphates ; ligand interactions ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Rate equilibrium dialysis was used to measure the binding of 2,3-diphosphoglycerate (DPG) to human oxy- and deoxyhemoglobin AO over the range pH 5-9, at 21.5°C. This approach yielded an accurate, precise, and self-consistent set of model-independent association constants. These data were successfully fitted to a thermodynamic model which is fuctionally similar to a Hill equation. The isotherms generated by this fitting procedure appear to intersect at low pH and converge at high pH. This apparent convergence at high pH is consistent with results obtained by oxygen equilibria studies performed under conditions of saturating DPG. These calculated isotherms were used to determine the enhancement of the Bohr effect as a function of pH. These results are consistent with data obtained by pH stat measurements by other investigators.This paper presents the first in a series of studies that will provide a systematic characterization of the interaction between hemoglobin and DPG.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prot.340010208
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    Paper (German National Licenses)
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