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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 2 (1992), S. 446-451 
    ISSN: 1432-1084
    Keywords: Biopsies, technology ; Kidney biopsy ; Liver biopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Open hepatic and renal biopsies were performed in 15 healthy pygmy pigs by each of 15 different commonly used needles/automated biopsy devices (guns). These biopsies were performed by three radiologists, each with widely varying prior experience in the use of each device. These 15 biopsy needles/biopsy guns were divided into six categories and compared in a multivariate model to assess differences in radiologist performance based upon their prior experience. The performance of individual radiologists varied the most with the group of aspiration needles. Even an experienced radiologist who had previously performed 55 such biopsies performed statistically worse than another radiologist who had performed in excess of 200. The biopsy guns, as a group, also demonstrated significant variability between radiologists and their experience level. However, when considered alone, experience appeared less a factor with the Bard 18-gauge (1.20 mm) long-throw biopsy gun. Considerable experience-related variability was also encountered in the liver with the Vim Silverman needle and in the kidney with the vacuum needles. The 14 gauge (2.00 mm) Tru-Cut needle provided a high-quality specimen seemingly independent of operator experience. Regardless of the needle or device used, prior experience in their use appears most important in biopsies of softer, less fibrous, and more vascular tissue.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric radiology 25 (1995), S. 1-6 
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In pediatric oncology, therapeutic decisions are made based on tumor response to chemotherapeutic agents. Sequential measurement of tumor bulk and its percent change on therapy must be accurately assessed. Will 3-dimensional (3-D) volumetric determination improve our ability to assess tumor response to therapy? Forty-five CT scans of pediatric patients with unresectable thoracic or abdominal neoplasia were assessed for tumor bulk by the standard “2-dimensional (2-D)” volume formula (cross-sectional areaxlength) and by 3-D volumetric analysis. Thirty-two examinations were performed in follow-up, and percent change in tumor size was calculated. The 2-D volume calculation overestimated tumor volume by more than 50% on all but two examinations when the 2-D volume was compared with the 3-D volume. In 28% of follow-up examinations, the 2-D calculation of percent change differed by more than 10% from the 3-D volume. Fifteen percent differed by over 25%. This changed the response category of one patient from “no response” to “partial response”. 3-D volumetric analysis, easily performed by a trained technologist, will give more accurate assessment of the actual tumor bulk and its subsequent changes in size in response to therapy. An additional, unexpected benefit of volumetric determination and its accompanying 3-D images was their use and enthusiastic acceptance by clinicians. Pediatric oncologists and surgeons used the sequential images in conferences with parents. In the future, graphic representations of tumor response to therapy might be used in determining the best time for second-look surgery or for other therapeutic manipulations.
    Type of Medium: Electronic Resource
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