ISSN:
1572-994X
Schlagwort(e):
Epstein-Barr virus
;
Burkitt's lymphoma
;
B-cell line
;
virus production
;
viral DNA
;
Southern analysis
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Abstract An Epstein-Barr virus (EBV)-producer line, designated Akata, was established from a Japanese patient with Burkitt's lymphoma. The Akata line possessed the Burkitt's-type chromosome translocation, t(8q-; 14q+), and was derived from the tumor cell. Akata cells produced a large quantity of transforming virus upon treatment of cells with anti-immunoglobulin antibodies (Takada, 1984). Southern blot analysis of viral DNA indicated that the Akata EBV is nondefective and more representative of wild-type viruses. Akata cells should be useful as a source of EBV.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00571929
Permalink