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  • 1
    Electronic Resource
    Electronic Resource
    Late response in exercise-induced asthma (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 14 (1984), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Eight subjects induced bronchospasm by free-range running. Four of these demonstrated a hue response at 5-6 hr after exercise. When compared lo the other group of four subjects, who also developed an early response but no late response, the difference in FEV1 at 5-6 hr was highly statistically significant. Although the phenomenon is not universally manifest it should no longer be held that there is no late response in exercise-induced asthma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1984.tb02210.x
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  • 2
    Electronic Resource
    Electronic Resource
    Paths to Success in the College Classroom
    Amsterdam : Elsevier
    Contemporary Educational Psychology 18 (1993), S. 464-478 
    Details
    ISSN: 0361-476X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Education , Psychology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1006/ceps.1993.1035
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  • 3
    Electronic Resource
    Electronic Resource
    The distribution of anionic sites on the surface of the chromaffin granule membrane
    Amsterdam : Elsevier
    Journal of Ultrasructure Research 55 (1976), S. 87-95 
    Details
    ISSN: 0022-5320
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0022-5320(76)80084-6
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  • 4
    Electronic Resource
    Electronic Resource
    Preparation and characterization of several molybdenum and tungsten hexaisothiocyanate complexes (1972)
    s.l. : American Chemical Society
    Inorganic chemistry 11 (1972), S. 1970-1972 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50114a056
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  • 5
    Electronic Resource
    Electronic Resource
    The adaptive da/dN method: a solution to the problem of processing crack growth data (2004)
    PO Box 1354, 9600 Garsington Road, Oxford OX4 2XG, UK. : Blackwell Publishing Ltd.
    Fatigue & fracture of engineering materials & structures 27 (2004), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The standard fatigue data-processing procedure, published in ASTM E647, is not adapted to the use of modern crack length measurement techniques. Because the use of this standard is usually required by journals, the raw data are often reduced to only a few data points. This way valuable information is simply thrown away and mathematical errors are unintentionally made. More importantly, the fact that no satisfactory reduction method exists, has led to destandardization of the processing procedure. Therefore, a new standard processing method is desired. In this paper a new data-processing method, referred to as the ‘adaptive da/dN method’, is proposed and discussed. This method is suitable for both optical and modern (electrical or automated) measurement techniques as well as modern (computer-assisted or -controlled) processing techniques. The adaptive da/dN method is validated both by data generated with a certain amount of scatter as well as actual experimental data. It shows a more accurate behaviour than the ASTM standards for all data types.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.2004.00795.x
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  • 6
    Electronic Resource
    Electronic Resource
    Amylase production by a Schwanniomyces occidentalis mutant in chemostat culture (1992)
    Springer
    Applied microbiology and biotechnology 37 (1992), S. 147-151 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary In carbon-limited chemostat culture the cell yields of a Schwanniomyces occidentalis mutant increased slightly from 0.58 g cells·g-1 starch at a dilution rate of 0.05 h-1 to 0.64 at 0.2 h-1. The maintenance energy requirement was 0.012 g starch·g-1 cells·h-1 and the critical dilution rate was 0.22 h-1 at 30° C. Specific α-amylase activity decreased with an increase in dilution rate. The specific activities of gluco-amylase and debranching activity initially increased with an increase in dilution rate up to 0.1 h-1, followed by a decrease in activity at higher dilution rates. Greatly higher levels of amylase activity were obtained in chemostat cultures than in batch cultures. The maximum temperature where a steady state was reached was 37° C, but production of amylases decreased with an increase in temperature. Amylase production was very sensitive to the dissolved oxygen tension (DOT), exhibiting a dramatic decrease at DOT values below 40% saturation. The critical DOT for growth was 31% of air saturation. On subjecting the mutant to anoxic conditions, growth as well as amylase production was arrested, but these continued after aeration was resumed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00178161
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  • 7
    Electronic Resource
    Electronic Resource
    Elastase α1 proteinase inhibitor complex, granulocyte count, ratio of immature to total granulocyte count, and C-reactive protein in neonatal septicaemiaproteinase inhibitor complex, granulocyte count, ratio of immature to total granulocyte count, and C-reactive protein in neonatal septicaemia (1992)
    Springer
    European journal of pediatrics 151 (1992), S. 353-356 
    Details
    ISSN: 1432-1076
    Keywords: Neonatal septicaemia ; Elastase α1 proteinase inhibitor ; Granulocyte ; C-reactive protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a prospective study elastase α1-proteinase inhibitor (Eα1PI), polymorphonuclear (PMN) count, the immature to total neutrophil count ratio (I/T ratio), and C-reactive protein (CRP) were analysed in 74 patients (76 cases) with neonatal septicaemia at the time of initial clinical symptoms. At that early stage of the disease, 94% of the patients had abnormal values for Eα1PI, 71% for I/T ratio, 61% for PMN count, and only 54% for CRP. PMN count was a poor indicator of septicaemia. Neutropenia, present in 26% of all patients, was related to normal Eα1PI in only 4 patients. The combined use of Eα1 and I/T ratio was the most sensitive indicator. In all patients irrespective of causative bacteria or disease onset at least one of these parameters was elevated. In early-onset septicaemia (n=31), normal CRP values occurred significantly more often (63%) than in late-onset sepsis (33%). Even in five of the seven fatal cases, initial CRP measurements were normal. The sensitivity of PMN count and I/T ratio did not differ significantly between early-and late-onset septicaemia. Laboratory changes observed in 18 newborns during the first 3 days of the septic episode show that the rate of pathological values for Eα1PI and I/T ratio was highest at the time of initial clinical symptoms and decreased on days 2 and 3. In contrast, CRP reached maximal values as late as day 2 (88% abnormal values), followed by a decrease on day 3. We conclude that the use of Eα1PI may improve the laboratory detection of neonatal septicaemia especially if used in combination with I/T ratio.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02113257
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  • 8
    Electronic Resource
    Electronic Resource
    Protein enrichment of grain sorghum by submerged culture of the amylolytic yeastsSchwanniomyces occidentalis andLipomyces kononenkoae (1992)
    Springer
    World journal of microbiology and biotechnology 8 (1992), S. 416-422 
    Details
    ISSN: 1573-0972
    Keywords: Amylase ; Candida utilis ; grain sorghum ; Lipomyces kononenkoae ; protein ; Schwanniomyces occidentalis ; starch ; yeast
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract Cultivation of aSchwanniomyces occidentalis derepressed mutant in a 10% (w/v) gelatinized grain sorghum slurry increased the crude protein content of the biomass from an initial value of 12% to 41% (dry) within 20 h, with no detectable residual starch. Co-cultivation ofCandida utilis with theS. occidentalis mutant improved the final crude protein content to 47% within 18 h, whereas a co-culture ofC. utilis with aLipomyces kononenkoae mutant resulted in a cultivation time of 50 h with a significantly lower protein content and a low final α-amylase activity. In a 15% (w/v) grain sorghum slurry aC. utilis/S. occidentalis co-culture increased the protein content to about 44% within 30 h. Yeast cultivation increased the lysine and threonine content of the final biomass considerably.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01198757
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  • 9
    Electronic Resource
    Electronic Resource
    Fine structure of initial outgrowth of processes induced in a pheochromocytoma cell line (PC12) by nerve growth factor (1979)
    Springer
    Journal of neurocytology 8 (1979), S. 493-511 
    Details
    ISSN: 1573-7381
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cells of the PC12 line (which is derived from a rat pheochromocytoma) develop neuron-like processes upon exposure to nerve growth factor (NGF), and thus provide an opportunity to study this phenomenonde novo. We have used the transmission electron microscope to analyse the early stages of process outgrowth (1, 2, 3 and 7 days) to determine what organelles are involved and in what sequence they appear during development. Despite the non-synchronous response to NGF, we can derive three main stages in early process formation. (1) NGF-treated cells develop conical extensions similar to, but larger and more numerous than those of controls. Extensions terminate in bulbous expansions that contain large number of chromaffin-like granules and bear microspikes filled with microfilaments. (2) The extensions of NGF-treated cells then acquire membranous organelles indicative of transmitter packaging and/or recycling of cytoplasmic membranes, for example, tubular reticulum, clear and dense-cored vesicles, multivesicular bodies, and lysosomes. (3) As processes elongate, they develop a shaft that contains an array of microtubules and fine tubular reticulum dispersed in a filamentous matrix, and varicosities that exhibit the same organelles seen in stage 2. The discussion stresses the similarities in the outgrowth of processes in PC12 cells and neurons, and speculates that NGF causes a change in organization and/or quantity of organelles that already exist in non-treated control cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01214805
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  • 10
    Electronic Resource
    Electronic Resource
    Reduction of Timed Hybrid Systems (1998)
    Springer
    Discrete event dynamic systems 8 (1998), S. 343-351 
    Details
    ISSN: 1573-7594
    Keywords: hybrid systems ; timed automata ; reduction ; finite state automaton
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract We consider a class of hybrid dynamical systems and obtain conditions under which the behavior of these systems can be reduced to a finite state automaton. Specifically, we consider timed automata with more general enabling regions coupling the continuous and discrete dynamics than those previously considered. We provide a necessary condition for the existence of a finite state reduction, together with examples showing that this condition is not sufficient. We then give two sufficient conditions that provide a large class of systems with general enabling regions which admit finite reductions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008385431572
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