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  • 1
    Electronic Resource
    Electronic Resource
    Repeated Clinical and Laboratory Examinations in Patients with an Equivocal Diagnosis of Appendicitis (2000)
    Springer
    World journal of surgery 24 (2000), S. 479-485 
    Details
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. In-hospital observation with repeated clinical examinations is commonly used in patients with an equivocal diagnosis of appendicitis. It is not known if repeated measurements of temperature and laboratory examinations have any diagnostic importance in this situation. The importance of repeated measurements of the body temperature, white blood cell (WBC) and differential cell counts, C-reactive protein concentration (CRP) and of the surgeon's repeated assessments was prospectively analyzed in 420 patients with an equivocal diagnosis of appendicitis at admission who were reexamined after a median of 6 hours of observation. The final diagnosis was appendicitis in 137 patients. After observation the inflammatory response was increasing among patients with appendicitis and decreasing among patients without appendicitis. The variables discriminating power for appendicitis consequently increased, from an area under the receiver operating characteristic (ROC) curve of 0.56 to 0.77 at admission, to 0.75 to 0.85 after observation. The ROC area of the surgeons' clinical assessment increased from 0.69 to 0.89. The WBC and differential cell counts were the best discriminators at the repeat examination. The change in the variables between the observations had weak discriminating power and had no additional importance in addition to the actual level at the repeat examination. To conclude, the diagnostic information of the temperature and laboratory examinations increased after observation. Repeated controls of the body temperature and laboratory examinations are therefore useful in the management of patients with equivocal signs of appendicitis, but the result of the examinations must be integrated with the clinical assessment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002689910076
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  • 2
    Electronic Resource
    Electronic Resource
    Diagnostic Value of Disease History, Clinical Presentation, and Inflammatory Parameters of Appendicitis (1999)
    Springer
    World journal of surgery 23 (1999), S. 133-140 
    Details
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00013174
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Fractures caused by muscle traction following lumbar myelography with meglumine iothalamate (Conray 60) and meglumine iocarmate (Dimer-X) (1974)
    Springer
    International journal of legal medicine 75 (1974), S. 219-224 
    Details
    ISSN: 1437-1596
    Keywords: Fraction of femoral neck, caused by muscle traction ; Traumatology, fractures caused by muscle traction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung In einem Fall wurden ausgedehnte Beckenfrakturen als Folge von Muskelkontraktionen nach lumbaler Myelographie mit Conray 60® beobachtet. Der Patient verstarb infolge einer massiven retroperitonealen Blutung und zeigte eine pulmonale Fettembolie. In einem anderen Fall trat eine Schenkelhalsfraktur nach einer lumbalen Dlyelographie mit Dimer-X® auf.
    Notes: Summary One case of extensive bilateral pelvis fractures as a result of muscle seizures following lumbar myelography with Conray 60 is described. The patient died from massive retroperitoneal hemorrhage and showed signs of so called pulmonary fat embolism secondary to the fractures. Also a case of fracture of the femoral neck following lumbar myelography with Dimer-X is reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01882705
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Blockage of the hepatic-artery blood flow by biodegradable microspheres (Spherex®) combined with local hyperthermia in the treatment of experimental liver tumors in rats (1985)
    Springer
    Journal of cancer research and clinical oncology 109 (1985), S. 38-41 
    Details
    ISSN: 1432-1335
    Keywords: Local hyperthermia ; Hepatic artery blockage ; Degradable starchmicrospheres ; Liver cancer ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of local hyperthermia and a simultaenous blockage of the hepatic-artery blood flow by degradable starch microspheres (Spherex®) was studied in a model of liver cancer in Wistar rats. Six days after each rat was inoculated with a cell suspension (NGW) in the central liver lobe, the rats were randomly allocated into four groups. The first group served as control, the second was treated with hyperthermia, the third by degradable starch microspheres (DSM) intraarterially, and the fourth with a combination of hyperthermia and DSM intraarterially. Tumor volumes were measured at laparotomy on days 0, 7, and 14. Temperature fluctuations in the tumor correlated well with those in the liver tissue, but were 2°–4° higher. The infusion of DSM did not change the pattern significantly. The tumor volumes were homogenous between the groups at the start of treatment. The tumor growth was significantly reduced compared with the control group at day 7 in group III (P〈0.05) and group IV (P〈0.01) but only in group IV at day 14 (P〈0.05). No differences in survival were found. Local hyperthermia concurrent with a blockage of the nutritional tumor blood flow seems to offer a more prominent and lasting tumor-growth inhibition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01884252
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    Paper (German National Licenses)
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