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  • 1
    Electronic Resource
    Electronic Resource
    The early effects of sympathectomy on bone blood flow (1984)
    Springer
    Calcified tissue international 36 (1984), S. 622-624 
    Details
    ISSN: 1432-0827
    Keywords: Sympathectomy ; Microspheres ; Bone blood flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Several laboratories, including our own, have investigated the physiology of bone blood flow by perfusion of the tibia via the nutrient artery. Any damage caused to the nerve supply by cannulation of the artery might affect the results. The possible effect of such damage was investigated by measuring blood flow to the dog tibia using a microsphere technique, before and after sympathectomy. No effect was found and the tibial nutrient artery is therefore a suitable vessel for perfusion when estimating nutrient exchange in bone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02405377
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  • 2
    Electronic Resource
    Electronic Resource
    Quantitative early phase scintigraphy in the prediction of healing of tibial fractures (1992)
    Springer
    Skeletal radiology 21 (1992), S. 241-245 
    Details
    ISSN: 1432-2161
    Keywords: Tibial fracture ; Technetium-99m methylene diphosphonate ; Bone blood flow ; Intramedullary nail ; External fixation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Imaging with technetium-99m methylene diphosphonate (99mTc-MDP) is established in the diagnosis of infection, neoplasia and ischaemic necrosis in orthopaedic practice, but its role in fracture healing is less well-defined. Previous studies have shown a relationship between fracture site activity (region A), activity in adjacent normal bone (region C) and time to union. The predictive value of the A/C ratio of the image obtained 300–800 s after injection was assessed in a prospective study of 50 patients with closed tibial fractures managed with plaster casts, external fixators and intramedullary nails. There were significant differences in absolute uptake and A/C ratio between the three groups (P〈0.05), but this was not related to time to union. Reamed nailing alters the distribution of 99m-Tc-MDP uptake so as to reduce the A/C ratio (1.10+0.20), but there is a promising role for early phase bone scanning in non-operative (A/C=1.40+0.21) or externally fixed (A/C=1.26+0.22) fractures in conjunction with other non-invasive methods of monitoring the biomechanical environment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00243065
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  • 3
    Electronic Resource
    Electronic Resource
    Instability of the cervical spine after anterior interbody fusion (1985)
    Springer
    Archives of orthopaedic and trauma surgery 104 (1985), S. 247-250 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 21 Patienten mit zervikaler Spondylose wurden durchschnittlich 27 ± 15 Monate nach einer unkomplizierten vorderen Fusion der Halswirbelsäule untersucht. Röntgenologisch fand sich bei 14 Patienten eine vordere Instabilität des angrenzenden Segments. Ihr Auftreten korrelierte nicht mit dem Alter und Geschlecht des Patienten, mit der Fusionsstrecke oder mit dem postoperativen Zeitraum. Anhaltende oder wiederkehrende Schmerzen konnten ebenfalls in keinen Zusammenhang mit der Instabilität gebracht werden.
    Notes: Summary Twenty-one patients suffering from cervical spondylosis and peripheral symptoms underwent uncomplicated anterior interbody fusion of the cervical spine and were re-examined clinically and radiologically at 27 ± 15 months (mean ± SD) after the operation. Translatory displacement of the segment adjacent to the fusion level was noted in 14 patients. Its incidence could not be related to the age and sex of the patient, to extent of the fusion, or to post-operative time. Anterior slippage did not correlate with persistent or recurring pain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00450219
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  • 4
    Electronic Resource
    Electronic Resource
    Lateral mass fusion for lower back pain (1987)
    Springer
    Archives of orthopaedic and trauma surgery 106 (1987), S. 381-384 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forty patients who underwent Wiltse's lateral mass fusion by two different surgeons for spondylolisthesis or degenerative disc disease have been independently reviewed. It was found at follow-up (mean 22 months ± S. D. 14 months) that factors that affected the final result were the age of the patient, the presence of preoperative nerve root symptoms, previous disc surgery, and incomplete fusion. The duration of symptoms, length of follow-up, preoperative spondylolysis, and the exent of the fusion did not appear to affect the result. This series confirms the previous reports that Wiltse's mass fusion is a good technique for relieving pain in the majority of patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00456874
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  • 5
    Electronic Resource
    Electronic Resource
    The effect of sympathomimetic drugs on bone capillaries (1986)
    Springer
    Archives of orthopaedic and trauma surgery 105 (1986), S. 62-65 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Da der Mineraltransport im Knochen von der Kapillardurchblutung in den Osteonen beeinflußt wird, haben gefäßaktive Substanzen orthopädische Bedeutung. Dieser Beitrag soll die Morphologie der Knochenkapillaren verdeutlichen und die Frage beantworten, ob Sympathomimetika die Häufigkeit durchströmter Kapillaren ändern können. Die quantitative Auswertung histologischer Serienschnitte von Mäuseknochen ergab keine signifikante Beeinflussung durch Phenylephrin. Im Hinblick auf elektronenmikroskopische Befunde scheinen postkapilläre Mechanismen den Blutfluß im Knochen zu regulieren.
    Notes: Summary Mineral transport to bone is dependant on an adequate blood supply. Thus, the role of vasoactive agents merits orthopaedic interest. This paper outlines the morphology of osteons and capillaries in cortical bone and discusses the possible morphological effects of systemic phenylephrine on mice tibiae. The frequency of dilated capillaries on histological serial sections did not significantly change. Hence, a postcapillary mechanism is likely to explain previous EM findings: i.e., an adrenaline-induced increase of the lumen diameter and perivascular cell edema.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00625663
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  • 6
    Electronic Resource
    Electronic Resource
    Two tools for integrating geology into ecosystem studies (1995)
    Springer
    Environmental geology 26 (1995), S. 246-251 
    Details
    ISSN: 1432-0495
    Keywords: Ecosystem ; Land management ; Matrix ; Hierarachy ; Geology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Increased interest in understanding ecosystems as a basis for land management requires new approaches for incorporating geology into the process. Limited work performed by geologists to ensure adequate information about geologic interrelationships with the biosphere is available to land managers and other earth scientists. This paper proposes two processes that will aid in increasing the amount and quality of geologic information available to land managers and other earth scientists. First, the geologic integration with ecosystem matrix is a computer data-base format presenting the chemical and physical interrelationships of geology with the biosphere. Second, the geologic terrane land unit hierarchy is an approach to segregating the earth's surface into a hierarchy of land units to simplify applying data-base information to the land.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00770475
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  • 7
    Electronic Resource
    Electronic Resource
    The role of skeletal blood flow in determining the uptake of99mTc-methylene diphosphonate (1983)
    Springer
    Calcified tissue international 35 (1983), S. 508-511 
    Details
    ISSN: 1432-0827
    Keywords: Radionuclide uptake ; Skeletal blood flow ; Capillary permeability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary The increased uptake of bone-seeking radionuclides following a fracture has been stated to be due to an increase in bone blood flow, resulting in an increase in capillary surface area available for exchange. This paper examines the relationship between the maximum instantaneous extraction of99mTc-MDP and blood flow in normal canine tibia. The findings, consistent with the model of capillary action proposed for muscle by Renkin and Crone, are applicable to bone. There is no evidence that in normal bone the surface area available for exchange responds to an increase in bone blood flow.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02405085
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  • 8
    Electronic Resource
    Electronic Resource
    Geometrical dimensions of the lower lumbar vertebrae – analysis of data from digitised CT images (2000)
    Springer
    European spine journal 9 (2000), S. 242-248 
    Details
    ISSN: 1432-0932
    Keywords: Key words Lumbar vertebrae ; Anatomical dimensions ; Spine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The precise dimensions of the lumbar vertebrae and discs are critical for the production of appropriate spinal implants. Unfortunately, existing databases of vertebral and intervertebral dimensions are limited either in accuracy, study population or parameters recorded. The objective of this study is to provide a large and accurate database of lumbar spinal characteristics from 126 digitised computed tomographic (CT) images, reviewed using the Picture Archiving Communication System (PACS) coupled with its internal measuring instrumentation. These CT images were obtained from patients with low back pain attending the spinal clinic at the Hammersmith Hospitals NHS Trust. Measurements of various aspects of vertebral dimensions and geometry were recorded, including vertebral and intervertebral disc height. The results from this study indicated that the depth and width of the vertebral endplate increased from the third to the fifth lumbar vertebra. Anterior vertebral height remained the same from the third to the fifth vertebra, but the posterior vertebral height decreased. Mean disc height in the lower lumbar segments was 11.6 ± 1.8 mm for the L3/4 disc, 11.3 ± 2.1 mm for the L4/5, and 10.7 ± 2.1 mm for the L5/S1 level. The average circumference of the lower endplate of the fourth lumbar vertebra was 141 mm and the average surface area was 1492 mm2. An increasing pedicle width from a mean of 9.6 ± 2.2 mm at L3 through to 16.2 ± 2.8 mm at L5 was noted. A comprehensive database of vertebral and intervertebral dimensions was generated from 378 lumbar vertebrae from 126 patients measured with a precise digital technique. These results are invaluable in establishing an anthropometric model of the human lumbar spine, and provide useful data for anatomical research. In addition this is important information for the scientific planning of spinal surgery and for the design of spinal implants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005860000140
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  • 9
    Electronic Resource
    Electronic Resource
    Measurement of blood flow to the vertebral bone and disc (1993)
    Springer
    European spine journal 2 (1993), S. 96-98 
    Details
    ISSN: 1432-0932
    Keywords: Débit sanguin ; Plateau vertébral ; Nutrition discale ; Blood flow ; Endplate ; Disc nutrition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Measurements of blood flow were made in the endplate and disc of the vertebrae in adult sheep. In anaesthetised animals, radioactively labelled microspheres were injected into the left ventricle and blood withdrawn from the brachial artery. The lumbar spine was then removed and sectioned to measure microsphere deposition. Blood flow in the bony endplate was found to be 4.22±0.59 ml/min 100g, and flow of 0.57±0.29 ml/min 100g was also measured in regions of the disc adjoining the endplate. No significant flow was recorded in the central region of the disc. This work has clinical significance in relation to spinal infections and also to the pathogenesis of degenerative disc disease.
    Notes: Résumé Des mesures du débit sanguin ont été réalisés au niveau des plateaux vertébraux et des disques chez le mouton adulte. Chez les animaux anesthésiés, des microagrégats ont été injectées dans le ventricule gauche et le sang a été prélevé au niveau de l'artère brachiale. Le rachis lombaire a été ensuite prélevé et découpé afin de mesurer la quantité de microagrégats déposée. Le débit sanguin au niveau des plateaux a été chiffré à 4.22±0.59 ml/mn/100g; un débit de 0.57±0.29 ml/mn/100g a été également relevé dans les zones discales adjacentes aux plateaux. Aucun débit significatif n'a été enregistré au niveau de la zone centrale du disque. Ce travail trouve son intérêt clinique dans les infections rachidiennes et aussi dans la pathogénie des affections discales dégénératives.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00302710
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Quantitative assessment of the motion of the lumbar spine in the low back pain population and the effect of different spinal pathologies on this motion (1997)
    Springer
    European spine journal 6 (1997), S. 308-315 
    Details
    ISSN: 1432-0932
    Keywords: Lumbar spine ; Spinal motion ; Normal population ; Low back pain population ; Diagnosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract There are few objective means by which disability caused by low back pain (LBP) can be quantified. The purpose of this study was to investigate the usefulness of motion measurements in the assessment of LBP. The motion characteristics of 138 LBP subjects were investigated, and the data compared with a previously published database of normal subjects. Values of range of motion and angular velocity were obtained for all subjects in each plane of motion. Analysis of these motion characteristics demonstrated significant differences (P 〈 0.0001) between the two populations; however both populations demonstrated considerable intersubject variation. Multiple regression analysis revealed that some of the variance in the LBP population was attributable to the underlying diagnosis. Patients with a spondylolisthesis tended to be hypermobile whilst those with spinal stenosis, disc prolapse or degenerative disc disease tended to be hypomobile. All diagnostic groups showed impairments in their velocity characteristics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01142676
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    Paper (German National Licenses)
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