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  • 1
    ISSN: 1619-7089
    Keywords: Xenon-133 ; regional ventilation ; activity breath ; number curve
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To evaluate the regional ventilation using 133Xe under different conditions, the respiratory flow and the phase with image were measured simultaneously, and sequential frames were made breath by breath. The flow signal and phase signal were converted to pulse signals by a microcomputer and stored with image data in the same file. Thus, the tidal volume and duration of each breath were measured. From sequential frames compiled breath by breath, an activity breath-number curve was made in each pixel, and the half-clearance breath number (B 1/2) was calculated. The changes in conventional half-clearance time (T 1/2) and B 1/2 were compared under different ventilatory conditions in normal subjects and in patients with chronic pulmonary emphysema. Values of B 1/2 indicated the change of turnover rate more accurately than T 1/2. It is considered that B 1/2 is a better parameter than T 1/2 for evaluating the change in regional ventilatory function under different conditions.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1615-2573
    Keywords: Heart failure ; Angina pectoris ; Vascular transmural pressure ; Aortic regurgitant fraction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A new finding of a segmental narrowing of the left anterior descending coronary artery in diastole (diastolic narrowing: DN) was reported. DN was found in 6 out of 45 patients (13.3%, 5 males, 1 female) with chronic aortic regurgitation (AR). It is likely that aortic regurgitation was more severe in terms of the history of heart failure, regurgitant fraction, left ventricular end-diastolic volume index and pressure, and aortic diastolic pressure in the patients with DN compared with those without DN. The phasic change of DN in cardiac cycles was analyzed by quantitative angiography, and indicated that DN commences at a point in mid-diastole when coronary vascular driving pressure (the instantaneous aortic and LV pressure difference) becomes abnormally reduced, reaches its maximum at end-diastole, and gradually recovers as aortic pressure increases during systole. In two patients, DN was no longer evident after valve replacement. We concluded that DN, a new coronary arteriographic finding, reflects the integrated severity of AR.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nuclear medicine 15 (1989), S. 646-648 
    ISSN: 1619-7089
    Keywords: 123I-IMP ; Lung dynamic scintigraphy ; Broncho-alveolar lavage ; Lung disease ; Lung dysfunction index
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The accumulation of venously injected 123I-IMP in the lung was studied. Between 30 and 50 min after the injection of the 1.5 mCi 123I-IMP, the concentration of 123I-IMP in the broncho-alveolar lavage fluid were much higher than in the blood. It was considered that 123I-IMP was transported into the alveolar spaces and was absorbed by the alveolar cells. The half time (T 1/2) of the 123I-IMP release from the lung between 10 and 25 min immediately after the injection was calculated. In normal subjects the T 1/2 ranged between 25 and 44 min and was prolonged in subjects with pulmonary fibrosis, sarcoidosis, and allergic alveolitis. It was considered that the retention of 123I-IMP was related not only to the endothelial cells, but also to the alveolar cells. It was considered that the analysis of the lung release of 123I-IMP forms a new lung dysfunction index.
    Type of Medium: Electronic Resource
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