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  • 1
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A haemolytic plaque-forming cell (PFC) assay detecting human B lymphocytes secreting IgG rheumatoid factor (RF) was established using sheep erythrocytes (SRBC) sensitized with rabbit IgG, developing rabbit anti-human IgG, and complement. IgG–RF PFC were only demonstrated with IgG–depleted guinea-pig serum as the source of complement. Cells spontaneously secreting IgG-RF were found among synovial fluid mononuclear cells (mean, 134/106) and synovial tissue mononuclear cells (mean, 1775/106) from patients with rheumatoid arthritis, whereas few were recorded among blood lymphocytes (mean, 3/106). The experiments revealed that the RF–IgG PFC were protein-synthesizing B lymphocytes. The antibody specificity of the secreted IgF-RF was verified by the inhibitory effect of exogenous human and rabbit IgG on PFC formation.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Copenhagen : Munksgaard International Publishers
    Scandinavian journal of medicine & science in sports 11 (2001), S. 0 
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: The objective was to estimate the prevalence of knee instability among active athletes and to investigate potential associations to type, amount and duration of sports participation. Based on a questionnaire, 339 athletes provided information about different features of occupation, sports activity and knee instability. The 12-month period prevalence of knee instability and constant or recurrent knee instability, and absence from sport and absence from work due to knee instability, was 22%, 14%, 5% and 1%, respectively. Knee instability as such, and constant or recurrent knee instability were found to be positively associated with female gender and different features of occupational work. In conclusion, knee instability is a commonly reported phenomenon among active athletes. It was found to be independent of the type and the amount of sports activity but highly dependent on female gender, type and amount of occupational work.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Copenhagen : Munksgaard International Publishers
    Scandinavian journal of medicine & science in sports 11 (2001), S. 0 
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: The present case–control study included as cases 24 athletes with anterior knee pain, and 17 controls, matching the cases according to gender and age. All cases had their most symptomatic knee examined by magnetic resonance imaging (MRI). Among controls one knee was chosen for examination at random. The MRI of the patella showed articular cartilage lesions in 17 out of 24 cases, whereas among the controls 4 out of 17 had articular cartilage lesions. (Odds Ratio 7.9 (95% confidence interval 1.9–33)). However, presence of articular cartilage lesions was not associated with duration of symptoms or intensity of the anterior knee pain. The present study showed a significant positive association between presence of articular cartilage lesions in the patella and presence of anterior knee pain, but further studies are needed to examine the relationship in detail.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of medicine & science in sports 9 (1999), S. 0 
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: The aim of the study was to estimate active knee flexion and active knee extension in athletes and to investigate the potential association of each to different types of sports activity. Active knee extension and active knee flexion was measured in 339 athletes. Active knee extension was significantly higher in women than in men and significantly positively associated with weekly hours of swimming and weekly hours of competitive gymnastics. Active knee flexion was significantly positively associated with participation in basketball, and significantly negatively associated with age and weekly hours of soccer. European team handball and swimming. The results point to sport-specific adaptation of active knee flexion and active knee extension.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of medicine & science in sports 9 (1999), S. 0 
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: The objective of the present cross-sectional study was to estimate one-leg standing balance in athletes and to investigate the relationship with type and amount of sports activity. The study comprised 339 active, competitive, non-pregnant athletes, aged 14–24 years from two sports clubs in the county of Aarhus, Denmark. The athletes answered a questionnaire about occupation and sports activity. One-leg standing balance was measured as the maximum time of one-legged balancing. The mean of the maximum time of one-legged balancing was 29 s (interquartile range 11.25–33.5 s). One-leg standing balance was positively associated with years of participation in basketball and was not associated with sex and age. We conclude that participation in basketball may induce significantly adaptive effects on standing balance.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0009-8981
    Keywords: Aggrecan ; ELISA ; Glycosaminoglycan ; Keratan ; Monoclonal antibodies ; Proteoglycan
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1437-160X
    Keywords: Interleukin ; Monocytes/macrophages ; Synovial fluid ; Rheumatoid arthritis ; Traumatic synovitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Interleukin-1 (Il-1)-like activity in biological fluids was measured by their ability to rectify the Il-1-dependent lymphokine production of highly purified T lymphocytes to a recall antigen. Il-1-like activity was found in 9 of 11 synovial fluid (SF) specimens from patients with rheumatoid arthritis (RA) but only in 2 of 11 paired RA sera. In traumatic synovitis, low Il-1-like activity was recorded in 5 of 9 SF specimens, and a similar low activity was found in sera of 4 of these patients. The Il-1-like activity was partly absorbed by an anti-Il-1 antibody. The presence of Il-1 in the SF of patients with RA suggests in vivo activation of monocytes/macrophages.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 46 (1981), S. 261-270 
    ISSN: 1439-6327
    Keywords: Glycogen ; Muscle fibre types ; Muscular fatigue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Five young males performed dynamic, submaximal contractions to exhaustion with the quadriceps muscle under arterial occlusion. The work load was 14.7 Watt (W). After 10 min rest with intact arterial circulation, the subjects commenced another bout to exhaustion; this process was repeated until a total of 10–16 bouts had been performed. Muscle biopsies were obtained immediately after the second, fifth, eighth, and last bout as well as 30 min after the last bout. The concentrations of adenosine triphosphate (ATP), creatine phosphate (CP), lactate, and glycogen were measured in each sample and some material underwent histochemical analysis. Muscle lactate was highest following the second work bout [22.9 mmol/kg wet weight (ww)] and gradually declined to 7.0 mmol/kg ww by the end of the last bout. CP level was low in all postexercise samples with the exception of a remarkably high CP (11.7 mmol/kg ww) after the last bout. Glycogen utilization tended to parallel muscle lactate levels, the rate of depletion being most rapid initially. Histochemical staining for glycogen depletion revealed that both type I and II fibres were low in glycogen, although type I was depleted most uniformly. In the first work bouts the high lactate and low CP levels in the total muscle could be responsible for the fatigue; none of these factors seem adequate to explain the development of the fatigue experienced in the later work bouts. It is concluded that muscle fatigue in this type of exercise is not related to substrate depletion or accumulation of metabolites, further that the fibre recruitment pattern is determined by the type and relative severity of performed work rather than local metabolic factors.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular histology 11 (1979), S. 737-740 
    ISSN: 1573-6865
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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