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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 51 (1982), S. 151-157 
    ISSN: 1432-1246
    Keywords: Styrene ; Methyl methacrylate ; Lung obstruction syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The main objective was to assess the biological effect of styrene and methyl methacrylate on the respiratory system in the industrial population. A total of 454 males from the exposed group and 683 workers from the control group were examined. The health status of the workers was evaluated by standardized interviews on chest symptoms and lung function testing. The environmental measurements were performed in all work places where the persons under study were employed. There was practically no differences in the prevalence of chronic chest symptoms in both groups of workers but the frequency of lung obstruction appeared to be more than twice as high among the exposed persons in comparison with the controls. A large proportion of cases with lung obstruction did not show any chronic chest symptoms. It appeared from the study that the environmental factor developed a much more harmful effect on lung function than smoking, and one effect was independent of the other.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 62 (1990), S. 311-317 
    ISSN: 1432-1246
    Keywords: Occupational air pollutants ; Epidemiology ; Respiratory tract diseases ; Urban population
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We analyzed the relationship between incidence rates of chronic respiratory symptoms over 13 years and occupational exposure during the first five years of follow-up. The study group contained 1132 males and 1598 females, 19 to 60 years of age, randomly selected from residents of Cracow, Poland. The data was collected in three surveys conducted in 1968, five and 13 years later. Prolonged occupational exposure (i.e. reported in the initial survey and 5 years later) to dusts doubled the odds for the appearance of chronic phlegm and attacks of breathlessness in all men, and of chronic bronchitis in men aged 41 to 50, initially free of the symptom. In women, this exposure doubled the odds for new chronic cough and for chronic bronchitis. Prolonged exposure to chemicals doubled the incidence rates of attacks of breathlessness and dyspnea in all women and of chronic bronchitis in women with the lowest level of education. Prolonged work in variable temperatures doubled the risk of wheeze in women. The effects of discontinuation or start of exposure during the initial 5 years of the study were also seen on the incidence rates of the symptoms but were less pronounced. The detected effects of occupational exposure were not modified by cigarette smoking or living in areas of the city with various levels of air pollution. This longitudinal analysis confirms the results of cross-sectional studies which have indicated deleterious effects of even moderate occupational exposures on respiratory symptoms.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 38 (1976), S. 61-67 
    ISSN: 1432-1246
    Keywords: Dust survey analysis ; Analysis of variance in the classification of environment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The paper presents the method of statistical analysis used for assessment of environmental data. The method is very useful and rather simple design for exploring in more detailed way the main sources of variation in the dust survey analysis. It is especially recommended in the course of epidemiological prospective observations.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 118 (1992), S. 276-282 
    ISSN: 1432-1335
    Keywords: Tobacco smoking ; Lung cancer ; Histological types ; Dose/responce analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In a population-based case/control study the differential lung cancer risk patterns due to tobacco smoking habits of various histological types have been investigated. The cases were 1432 deaths from lung cancer in the years 1980–1987, of which the histological type was known for 627 individuals. There was 54% squamous cell carcinoma, 24% small-cell carcinoma and 17% adenocarcinoma. Controls were 1343 deaths from other causes. Next-of-kin interviews were performed. The results of the study confirmed that cigarette smoking is associated with all histological types of lung cancer; however, the dose/response relationship between smoking and adenocarcinoma differed clearly from that observed in squamous and small-cell carcinomas. In the latter histological types the gradient of risk was much stronger as the number of cigarettes smoked or duration of smoking increased. The overall relative risk for smoking in small-cell and squamous cell carcinoma was 15.4 and 13.5 respectively, whereas that for adenocarcinoma was weaker (relative risk=3.1). An interesting difference between squamous and small-cell carcinomas was found also for patients who gave up smoking. The effect of stopping was more pronounced in squamous cell carcinoma. The attributable risks for smoking in squamous and small-cell carcinoma were much higher (90% and 88% respectively) than for adenocarcinoma (64%). The data suggest that adenocarcinoma is likely to be related to other factors than tobacco smoking to a greater extent than are squamous or small cell carcinoma. Possible sources of bias, such as missing histological diagnoses, are discussed in detail.
    Type of Medium: Electronic Resource
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