ISSN:
0170-2041
Keywords:
Acetylation, enzymatic
;
2-Propanol, (+)-1-phthalimido
;
Propane, (+)-2-acetoxy-1-(phthalimido)-
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Enzymatic Acetylation of (±)-1-Phthalimido-2-propanol1-Phthalimido-2-propanol [(±)-1] is an N-protected derivative of 1-amino-2-propanol. By irreversible enzymatic acetylation of the racemate (±)-1, (+)-2-acetoxy-1-(phthalimido)propane [(+)-2] and (+)-1-phthalimido-2-propanol [(+)-1] have been isolated on a preparative scale in good optical and chemical yields. Both optically active compounds are useful chiral intermediates.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1990199001188
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