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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 61 (2002), S. 0 
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Egg cannibalism near the sea bottom was observed in herring Clupea harengus at the end of the spawning season. About 10% of the individuals had consumed eggs and egg feeders were predominantly spent males.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 56 (2000), S. 0 
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: During October-January in a northern Norwegian fjord system and in February-March at the main western Norway spawning grounds, an index IG of gonad weight of spring-spawning herring Clupea harengus in percentage of expected gonad weight at full maturity for a given total length LT, tended to increase with LT in the range 27–31 cm as the proportion of recruit spawners decreased. Insignificant differences in IG were found between LT groups in the range 32–37 cm (repeat spawners). This is contrary to that suggested in other studies and signifies that generally the stock spawns in only two waves, repeat spawners first and the recruit spawners second. IG also increased with somatic and total condition factor, which signifies that spawning time may be influenced by summer feeding conditions.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Sjögren's syndrome (SS) is an autoimmune rheumatic disorder characterized by chronic lymphocytic infiltration and decreased secretion in the salivary glands (SGs). For some time, apoptosis has been suggested to constitute the major mechanism for acinar epithelial destruction during the effector phases; however, this is still controversial. We have recently demonstrated that despite the expression of Fas and FasL, the incidence of apoptosis is not increased in SS patients compared with control individuals. Our aim was therefore to further evaluate the expression of the pro- and anti-apoptotic Bax and Bcl-2 proteins. CD40 and CD154 expression was also investigated, as CD40 ligation has been suggested to protect cells from Fas-mediated apoptosis. Immunohistochemical staining was performed on SG tissue from primary and secondary SS patients, a group of patients with non-SS-related degenerative changes as well as on healthy control individuals. The frequency of stained cells in the foci of infiltrating mononuclear cells (IMCs) and in the acinar and ductal epithelium was determined. We found the expression of Bcl-2 but rarely Bax in SS SG IMCs. Bcl-2 in epithelial cells was sparse, while Bax expression occurred frequently and with no significant difference between the patient groups. CD40 and CD154 expression was high among SS IMCs, while CD40 levels were slightly decreased in SS epithelium compared with controls. Elevated CD154 expression was found in SS epithelium, being significantly increased in the ducts. In conclusion, our study further supports the hypothesis about apoptosis resistance among SS focal IMCs and suggests a putative protective role of CD40 ligation in SS SG epithelium.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 5 (1976), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Antibodies to human IgG (rheumatoid factors (RF)) from serum Han resembled the ‘intermediate’ complexes of sera from some patients with rheumatoid arthritis. These RF were isolated from heat-inactivated serum by affinity chromatography on agarose-coupled human IgG. Indirect immunofluorescence revealed that the isolated RF cross-reacted with cell nuclei from many species. Virtually all the antinuclear factor (ANF) activity of this serum was extracted by IgG-agarose. Alternative explanations of this phenomenon, such as nonspecific binding of a separate population of ANF, binding of ANF to the immunosorbent via an IgG RF-IgG ANF immune complex, or presence of nuclear antigens on the immunosorbent, were ruled out. The cross-reacting antibodies possessed both k and λ light chains and predominantly γ and some μ heavy chains, indicating that they were of polyclonal origin. The antinuclear activity was present in the F(ab′)2 fragments. The interpretation of this strange cross-reaction is briefly discussed.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 42 (1995), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Sialadenitis develops spontaneously in MRL/Mp mice bearing a lymphoproliferative gene, lpr (MRL/ Mp-lpr/lpr). Based on recent observations of an oligoclonal expansion of T-cell receptor (TCR) expressing Vβ chain families (Vβ4, Vβ8.1, 2, Vβ10b) in salivary glands of these mice we have initiated selective antibody therapy. Treatment with monoclonal antibodies (MoAb) specific for T cells expressing a mixture of TCR Vβ4, Vβ8.1, 2 and Vβ10b was applied to MRL/lpr mice before and after the spontaneous development of Sialadenitis. The in vivo treatment with Vβ4, Vβ8.1, 2 and Vβ10b MoAb did not prevent the development of Sialadenitis. However, in animals with established Sialadenitis, treatment with the MoAb significantly decreased the inflammation compared with the control groups, Immuno-histochemical staining of cell phenotypes demonstrated a change in the ratio of CD4/CD8 in the animals with established Sialadenitis. Altogether, these findings illustrate that it is possible to modulate Sialadenitis and infiltrate cell phenotypes in vivo in MRL/lpr mice with specific anti-TCR Vβ MoAb treatment.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Munksgaard : Munksgaard International Publishers
    Journal of clinical periodontology 26 (1999), S. 0 
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. The replacement of teeth by means of titanium implants is a safe and predictable procedure in most patients. Some studies show that a small number of patients lose the majority of their implants. Unfortunately, it is impossible to identify these patients prior to surgery. It is important to report such cases so that we may, in the future, be able to identify them before surgery. The present case showed a severe and rapid exfoliation of titanium implants. Out of 8 implants inserted in the anterior lower jaw of this patient, only two maintained osseointegration over a 2-year period.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Fisheries Research 11 (1991), S. 155-170 
    ISSN: 0165-7836
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Fisheries Research 16 (1993), S. 147-163 
    ISSN: 0165-7836
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 17 (1990), S. 0 
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Biopsy specimens were taken at gingivectomy from 18 adult patients undergoing treatment for chronic marginal periodontitis. They were embedded so that the cut surface of the gingiva was parallel to the top of the block to obtain a comprehensive view in a transversal plane of the inflammatory cell infiltrate near the bottom of the pocket. Sections were stained with HES or with toluidine blue for histological description, and acid α-naphthyl acetate esterase (ANAE) was used to differentially stain T lymphocytes, plasma cells and monocytes/macrophages. Sections stained with HES showed that the density and size of the cell infiltrates varied along the circumference of a tooth over very short distances and on various surfaces on neighbouring teeth. Differential counts of cells stained for ANAE demonstrated great variation in the composition of the cell infiltrates, particularly along the pocket epithelium. The predominating ANAE positive cell type in this area was T lymphocytes, while in the central connective tissue, plasma cells predominated. There was no systematic covariation between the localization of the gingiva (i.e. mesial, facial, etc.) and the composition of the cell infiltrates. The local variation in the composition of the cellular infiltrate most likely reflects local variability in the noxious substances (i.e. plaque composition) within the periodontal pocket, and in the resulting local inflammatory response.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 51 (1997), S. 0 
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Newly hatched autumn-spawned herring larvae Clupea harengus were released in two 2500-m3 outdoor mesocosms and reared over a 2-month period. Hydrographic conditions were similar in the two mesocosms, but the average plankton density was initially more than 10 times higher in mesocosm B compared to mesocosm A (〉11−1v. 〈0.11−1). Half-way through the experiment the feeding conditions reversed with three times higher average densities in mesocosm A than in mesocosm B (〉31−1v.∼11−1). Herring larvae were sampled with a 0.3-m2 two-chambered net twice weekly, and survivors were harvested by draining the mesocosms at the end of the experiment. Otolith growth trajectories of individual larvae were determined by relating radial otolith size with number of increments from the outer edge of the otolith (days before capture). The increment widths during the first 3 weeks after hatching, including the first-check size, were generally wider among larvae from mesocosm B (relatively good initial feeding conditions) than among those from mesocosm A (poor initial feeding conditions). The otolith growth pattern also confirmed that the surviving herring in mesocosm A belonged to the upper size range of larvae in the mesocosm after only 2–3 weeks from hatching; no such trend was found in mesocosm B. In both mesocosms the otolith size-at-age indicated that with the present sampling gear, herring larvae larger than 20–25 mm were underrepresented in the net samples. The information obtained from otolith-size-at-age is compared with other morphometric and biochemical measures of size and condition of larvae obtained throughout the experiment.
    Type of Medium: Electronic Resource
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