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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 8 (1960), S. 193-196 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 35 (1997), S. 0 
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: Predictive ground-water flow modeling may be simplified by application of superposition when the governing equations are linear. The simplification allows evaluation of impacts of individual aquifer stresses and minimized model input, output, and interpretation. Modeling is performed by using (1) boundary conditions and aquifer properties provided by previous calibrations or analytical techniques, (2) setting the initial potentiometric surface and prescribed-head boundaries to an arbitrary horizontal datum, and (3) simulating a specific recharge or discharge stress.Superposition was applied to an existing, calibrated model of the Snake River Plain aquifer to simplify prediction of changes in interaction with the Snake River. Simulations predict the temporal relationships between ground-water use at multiple locations within the Snake River Plain and surface-water depletion in four hydraulically connected reaches of the Snake River. Simulated aquifer water use at a location approximately five miles from a hydraulically connected river reach results in river depletions greater than 80% of the pumping rate after 10 years. Water use further than 50 miles from hydraulically connected river reaches results in depletions from 10 to 30% of the annual average pumping rate after 100 years. Results present spatial and temporal impacts of water uses on the Plain that are conceptually and quantitatively beneficial to water resources planners and water users.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biochemistry 44 (1975), S. 491-522 
    ISSN: 0066-4154
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Chemistry and Pharmacology , Biology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Further studies on the processing and use of animal-bone-derived calcium phosphate materials in biomedical applications are presented. Bone powders sourced either from the direct crushing and milling of bovine, ovine and cervine bone or after being subjected to defatting and acid digestion/NaOH reprecipitation and sodium hypochlorite hydrogen peroxide treatment of animal bones were characterized using Fourier transform infra-red (FTIR) spectroscopy, 13C solid state magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy, atomic absorption (AA) and inductively coupled plasma (ICP) spectrometric techniques. Bone powders were trialled for their potential use as a substrate for phosphine coupling and enzyme immobilization as well as a feedstock powder for plasma spraying on titanium metal substrates. Results indicated that enzyme immobilization by phosphine coupling could be successfully achieved on milled cervine bone with the immobilized enzyme retaining some activity. It was found that the presence of impurities normally carried down with the processing of the bone materials (viz., fat and collagen) played an important role in influencing the adsorbency and reactivity of the powders. Plasma spraying studies using reprecipitated bovine-derived powders produced highly adherent coatings on titanium metal, the composition of which was mostly hydroxyapatite(Ca10(PO4)6(OH)2) with low levels of α-tricalcium phosphate (α-Ca3(PO4)2) and tetracalcium phosphate (Ca4P2O9) also detected. In general, animal derived calcium phosphate materials constitute a potentially cheaper source of calcium phosphate materials for biomedical applications and make use of a largely under-utilized resource from abattoir wastes. © 2000 Kluwer Academic Publishers
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The acid β-galactosidase cDNA of Portuguese Water dogs was isolated and sequenced. The entire coding region of the gene consists of 2004 nucleotides encoding a protein of 668 amino acids. Its encoding sequence indicates approximately 86.5% identity at the nucleotide level and about 81% identity at the amino acid level with the encoding region of the human acid β-galactosidase gene. The deduced amino acid sequence contains a 24-amino-acid putative signal sequence, six possible glycosylation sites, and seven cysteine residues. A homozygous recessive mutation, causing canine GM1-gangliosidosis, was identified at nucleotide G200→A in exon 2 resulting in an Arg60→His (mutation R60H) amino acid substitution. The mutation creates a new restriction enzyme site for Pml1. Genotyping 115 dog samples for this acid β-galactosidase gene alteration readily distinguished affected homozygous recessives (n=5), heterozygous carriers (n=50) and normal homozygotes (n=60). DNA mutation analysis provided a method more specific than enzyme assay of β-galactosidase for determination of carriers.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Conversion of bovine cancellous bone to a useful biomedical xenograft material involves several processing steps which include boiling, defatting and deproteination (i.e. bleaching). This study has shown how these processes can influence cancellous bone modulus and strength. It was found that prolonged boiling in water for six hours followed by NaOCI bleaching had a deleterious effect on the overall strength of the bovine bone. In contrast, bone samples subjected to only moderate boiling (1.5 hours) exhibited a 22% stiffness increase due mainly to the effects of drying. The same stiffened samples, when subjected to the bleaching procedure, retained some strength with only a small reduction in moduli values. It can be concluded that careful control of defatting and bleaching procedures on bovine bone is able to give a strong, albeit, brittle material with preservation of the original bone architecture. The bone xenograft materials are worthy of further investigation in in vivo clinical trials to assess their performance in contact with biological fluids. © 2000 Kluwer Academic Publishers
    Type of Medium: Electronic Resource
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