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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical psychology 7 (2000), S. 0 
    ISSN: 1468-2850
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Psychology
    Notes: Joiner (this issue) outlines an organizational framework of dysfunctional psychological processes observed in unipolar major depressive disorder (MDD) patients, which he hypothesizes makes substantial contributions to the chronicity of this common and disabling disorder. Rather than concentrating on the clinical characteristics, past history, biological markers, or genetic variables as risk factors for chronicity, Joiner references the scarring effects of repeated episodes and a set of destructive interpersonal processes present in depressed patients that he feels promotes depressive chronicity. This extends observations reported in prior studies on psychosocial disability in depression, which have concentrated primarily on such issues as employment status, estimates of well-being, and so on, whereas Joiner emphasizes psychological disability and disrupted interpersonal relationships.This commentary introduces a new dimension of chronicity of unipolar MDD that involves the long-term, chronic manifestation of depressive symptomatology, in addition to the frequent major depressive episode relapse. Further, the long-term symptomatic structure of unipolar MDD is described as a dimensional continuum of symptom severity and illness activity and then highlighted as to the relevance of both of these newer concepts to Joiner's proposals. A number of interesting research questions are outlined in by Joiner that need empirical validation but, if answered, could make a contribution to the understanding and reduction of depression chronicity.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2072
    Keywords: Methylphenidate ; Route of administration ; Oral ; Intravenous ; Behavioral activation ; Pulse ; Blood pressure ; Growth hormone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Oral methylphenidate (1.0 mg/kg) and intravenous methylphenidate (0.5 mg/kg) were compared as to their ability to increase behavioral activation, pulse, blood pressure, and serum growth hormone. Intravenous methylphenidate was considerably more effective than oral methylphenidate in activating behavior and in increasing pulse and blood pressure. Although oral methylphenidate appeared to increase behavioral activation, this effect was not statistically significant.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2072
    Keywords: Naloxone ; Methylphenidate ; Attenuation ; Euphoria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of naloxone on IV methyl-0henidate-induced mood, behavior, and neurohumoral changes were assessed in eight psychiatric inpatients. While methylphenidate alone produced anticipated changes, the indications for significant naloxone-methylphenidate interactions were minimal. It is speculated that larger doses of naloxone might be required to produce modification of the psychostimulant effects.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2072
    Keywords: Lithium ; Methylphenidate ; Neurohormones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Evidence is presented which suggests that lithium modifies the mood and behavioral alterations resulting from IV methylphenidate. Specifically, lithium significantly reduces the level of arousal-activation, euphoria-grandiosity, and the total score of manic-state ratings following a methylphenidate challenge. In addition, lithium appears to be capable of modifying the growth hormone response to methylphenidate.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 61 (1979), S. 203-206 
    ISSN: 1432-2072
    Keywords: Interpersonal interactions ; Marijuana ; Delta-9-tetrahydrocannabinol ; Affective sensitivity ; Emotions ; Perception
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The influence of marijuana on the ability to perceive emotions in others was studied in 30 male volunteers who were experienced marijuana users. Subjects smoked either placebo or active marijuana containing 6 mg Δ 9. The Affective Sensitivity Scale, a test developed to measure the ability to perceive emotions in others, was divided at midpoint and the two halves were administered before and after smoking, respectively. Analysis of variance demonstrated a decline in test scores following active marijuana administration, while changes following the placebo treatment were not significant.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Electrophysiological measures of selective attention were obtained in a selective listening paradigm developed by Hillyard and associates6-8. Auditory event-related potentials (AERPs) were recorded from subjects who listened selectively to sequences of discrete tones delivered in random order ...
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-2072
    Keywords: Schizophrenia ; Phenothiazines ; Coping ; Word Association
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The paper presents evidence concerning the stability and sensitivity of three classes of behavioral measures: a) word association quality, b) perceptual coping style, and c) skin resistance level and reactivity across a 21-day interval. Acute schizophrenic males were administered these measures 7 and 28 days following admission to a State hospital. Half of the patients were assigned to active phenothiazine medication at 7 days and half continued on placebo. Comparison of correlations between 7- and 28-day data for drug and placebo groups revealed different patterns of stability across time and sensitivity to drug ingestion for each of these three classes of measures.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 52 (1977), S. 307-309 
    ISSN: 1432-2072
    Keywords: Toxicity ; Lithium ; Acetylcholine ; Cholinergic ; Physostigmine ; Cholinesterase inhibitor ; Drug interactions ; Scopolamine ; Anesthesia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The interaction between the reversible cholinesterase inhibitor, physostigmine, and lithium chloride was studied in adult male rats. A combination of lithium plus physostigmine increased lethality more than that caused by either physostigmine or lithium alone. Scopolamine completely reversed this effect. These drug interactions may have clinical significance, since lithium plus cholinesterase inhibitors may be used together in the practice of medicine.
    Type of Medium: Electronic Resource
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