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  • 1
    Electronic Resource
    Electronic Resource
    The effect of carotid sinus denervation on fetal heart rate variation in normoxia, hypoxia and post-hypoxia in fetal sheep (1997)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 104 (1997), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To investigate whether carotid sinus nerve reflexes are linked to the increase in heart rate variation in acute (one hour) hypoxia in late gestation fetal sheepDesign Comparison of short term variation between intact and carotid sinus denervated fetuses in normoxia, hypoxia and post-hypoxia.Subjects Sixteen chronically catheterised pregnant sheep in late gestation.Results There was no significant difference in short term variation between intact and denervated fetuses in normoxia. In intact fetuses short term variation increased significantly in hypoxia. In denervated fetuses it tended to increase in hypoxia, but this was not statistically significant. During the post-hypoxia period, short term variation increased significantly in denervated fetuses, although at this time it was decreasing in intact fetuses. When the decrease in pH was small intact fetuses showed a significantly greater increase in short term variation than denervated fetuses in hypoxia. In contrast, short term variation increased similarly in both groups when the pH decrease was greater (〉 0.03 in early hypoxia and 〉 0.05 in late hypoxia).Conclusions Carotid sinus nerve reflexes have an important influence on heart rate variation in hypoxia and post-hypoxia. It appears that other mechanisms (e.g. a rise in circulating catecholamines) are linked to an increase in heart rate variation when mild acidemia occurs in hypoxia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1997.tb11498.x
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  • 2
    Electronic Resource
    Electronic Resource
    Neuro-Behçet's disease showing severe atrophy of the cerebrum (1976)
    Springer
    Acta neuropathologica 34 (1976), S. 95-103 
    Details
    ISSN: 1432-0533
    Keywords: Neuro-Behçet's disease ; General atrophy of the cerebrum ; Perivascular softenings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 38-year-old female died 6 years after the onset of what was, clinically and histopathologically, consistent with Neuro-Behçet's disease. Pathologically the cerebrum showed severe atrophy. The main changes were observed in the grey and white matter, the diencephalon and the basal ganglia by light microscopy. All these changes originated in softenings around blood vessels, especially small vessels or capillaries. These foci fused together to form large regions of softening. Glial or mesenchymal reactions were minimal. In the white matter there was slight perivascular-infiltration, mainly consisting of lymphocytes. In view of these findings, it is suggested that these changes were caused by an allergic vasculitis. The present case of Neuro-Behçet's disease is the first one showing general atrophy of the cerebrum. It is very important in relation to demyelinating encephalitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00684660
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    Paper (German National Licenses)
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