ISSN:
1619-1560
Keywords:
multiple system atrophy
;
parkinsonism
;
cerebellar ataxia
;
autonomic insufficiency
;
urinary dysfunction
;
glial cytoplasmic inclusions
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We report the results of a consensus conference on the diagnosis of multiple system atrophy (MSA). We describe the clinical features of the disease, which include four domains: autonomic failure/urinary dysfunction, parkinsonism and cerebellar ataxia, and corticospinal dysfunction. We set criteria to define the relative importance of these features. The diagnosis of possible MSA requires one criterion plus two features from separate domains. The diagnosis of probable MSA requires the criterion for autonomic failure/urinary dysfunction plus poor levodopa responsive parkinsonism or cerebellar ataxia. The diagnosis of definite MSA requires pathological confirmation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02309628
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