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Digitale Medien

Chemotaxis of freshly separated and cultured human keratinocytes (1994)

GYULAI, R. ; HUNYADI, J. ; KENDERESSY-SZABÓ, A. ; [weitere]

Oxford, UK : Blackwell Publishing Ltd

Clinical and experimental dermatology 19 (1994), S. 0

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ISSN: 1365-2230

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Medizin

Notizen: It is generally accepted that keratinocyte migration plays a critical role in the process of wound healing. A study was therefore made of the migratory response of freshly separated and cultured human keratinocytes to factors with chemotactic properties for a variety of cells. Interleukin-lα (IL-lα), interferon-γ (IFN-γ), interleukin-8 (IL-8), and tumour necrosis factor α (TNF-α) were tested for their chemotactic effectiveness in a modified Boydcn chamber assay. IFN-γ, IL-lα and IL-8 were demonstrated to serve as chemoattractants for freshly separated keratinocytes. For cultured cells, however, only IFN-γ was found to display chemotactic properties. The findings demonstrate that there is significant difference between the chemotactic behaviour of freshly separated and cultured cells.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1111/j.1365-2230.1994.tb01201.x

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