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  • 1
    Electronic Resource
    Electronic Resource
    Algorithms for combining menstrual and ultrasound estimates of gestational age: consequences for rates of preterm and postterm birth (2002)
    Oxford, UK : Blackwell Science Ltd
    BJOG 109 (2002), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We compared rates of preterm and postterm birth according to six algorithms for gestational age (GA) estimates based on last menstrual period (LMP) and early ultrasound (EUS): LMP alone, LMP if the discrepancy between the two estimates was within 14 days and otherwise EUS (14-day rule), a 10-day rule, a seven-day rule, a three-day rule and EUS alone. In a sample of 44,623 births in a Canadian tertiary hospital, the choice of algorithms makes a substantial impact on both preterm and postterm birth rates, even when EUS was used for discrepancies over two weeks.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.2002.01068.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Determinants and consequences of discrepancies in menstrual and ultrasonographic gestational age estimates (2005)
    Oxford, UK and Malden, USA : Blackwell Science Ltd
    BJOG 112 (2005), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives  To assess the association between maternal and fetal characteristics and discrepancy between last normal menstrual period and early (〈20 weeks) ultrasound-based gestational age and the association between discrepancies and pregnancy outcomes.Design  Hospital-based cohort study.Setting  Montreal, Canada.Sample  A total of 46,514 women with both menstrual- and early ultrasound-based gestational age estimates.Main outcome measures  Positive (last normal menstrual period 〉 early ultrasound, i.e. menstrual-based gestational age is higher than early ultrasound-based gestational age, so that the expected date of delivery is earlier with the menstrual-based gestational age) discrepancies ≥+7 days, mean birthweight, low birthweight, stillbirth and in-hospital neonatal death.Results  Multiparous mothers and those with diabetes, small stature or high pre-pregnancy body mass index were more likely to have positive discrepancies. The proportion of women with discrepancies ≥+7 days was significantly higher among chromosomally malformed and female fetuses. The mean birthweight declined with increasingly positive differences. The risk of low birthweight was significantly higher for positive differences. Associations with fetal growth measures were more plausible with early ultrasound estimates.Conclusions  Although most discrepancies between last normal menstrual period- and early ultrasound-based gestational age are attributable to errors in menstrual dating, our results suggest that some positive differences reflect early growth restriction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.2004.00311.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Adverse Drug Reactions in Dermatologic Therapy (1981)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of dermatology 20 (1981), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-4362.1981.tb04908.x
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  • 4
    Electronic Resource
    Electronic Resource
    Adaptive Formation of Fatty Acid Activating Enzyme in Chilomonas paramecium (1969)
    Oxford, UK : Blackwell Publishing Ltd
    The @journal of eukaryotic microbiology 16 (1969), S. 0 
    Details
    ISSN: 1550-7408
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: SYNOPSIS. Chilomonas paramecium contains 2 different fatty acid activating enzymes (FAAE), one of which utilizes acetate as a substrate, while the other catalyzes the reaction with either butyrate or hexanoate. The site of greatest activity of these enzymes was found to be not in the mitochondrion, but in the “soluble” portion of the cell. Synthesis of acetyl FAAE is constitutive; this enzyme is present regardless of the substrate in the growth medium.The synthesis of the butyryl-hexanoyl FAAE is induced by the presence of either of the substrates. The details of induction of the butyryl enzyme in acetate-grown cells, and the de-adaptation of cells grown in butyrate and transferred to acetate, are given. One mole of pyrophosphate is produced for each mole of CoA-SH reacting, (thus establishing the prevalence of the acyl-adenylate pathway in Chilomonas fatty acid activation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1550-7408.1969.tb02272.x
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    Paper (German National Licenses)
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