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  • 1
    Digitale Medien
    Digitale Medien
    Asymptomatic isolated microhaematuria: natural history of 136 children (1991)
    Springer
    Pediatric nephrology 5 (1991), S. 578-581 
    Details
    ISSN: 1432-198X
    Schlagwort(e): Urine screening ; Asymptomatic haematuria ; Isolated haematuria
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract In a mass screening programme, 251 children with isolated microhaematuria were detected. Of these 251 children, 115 were excluded from the study because of microhaematuria, secondary to a specific cause. The remaining 136 children were diagnosed as having asymptomatic isolated microhaematuria (ASH). Of these 136 children, 23 had evidence of urinary abnormalities in their family members. Red blood cell casts were evident in 31 children at their initial visit or during the follow-up period. Ten children had one or more episodes of macrohaematuria during the study. Renal biopsy was performed in 19 children because of indications of glomerular discase, and 13 of these 19 children had mild to moderate glomerulonephritis. None of these 136 children developed hypertension or renal impairment after a mean period of 7.4 years (range 6–13 years). Thirty-five children had normal urinary findings within 6 years of their initial visit, and 100 have had persistent microhaematuria, without proteinuria throughout the follow-up period. The other child had microhaematuria with proteinuria greater than 1 g/m2 per day at the end of the study. This study suggests that the prognosis of ASH is good and that renal biopsy is not indicated for children with ASH.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00856642
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  • 2
    Digitale Medien
    Digitale Medien
    Immune status of children on continuous ambulatory peritoneal dialysis (1992)
    Springer
    Pediatric nephrology 6 (1992), S. 179-181 
    Details
    ISSN: 1432-198X
    Schlagwort(e): Immunity ; Chronic renal failure ; Vaccination
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Immunological parameters including serum IgG, IgA and IgM, lymphocyte phenotypes (CD3, CD4, CD8, HLA-DR+CD3-), natural killer cell activity and lymphocyte proliferation with phytohaemagglutinin were assessed in 10 children on continuous ambulatory peritoneal dialysis (CAPD) and 10 control subjects. Live vaccines were injected into 6 of the 10 children on CAPD (4 had a combined measles-mumps-rubella vaccine and the other 2 mumps vaccine). Serum antibody titres to these viruses were measured before and after vaccination. The serum IgG level was statistically lower in the CAPD group than in the control group (P〈0.01), but there was no difference in the percentage of HLA-DR+CD3-cells and in the ratio of CD4 to CD8 between the two groups. There were no differences in the other parameters between the two groups. All of the 6 vaccinated children seroconverted, and serious side effects were not noted. Our results suggest that children on CAPD have no significant immune impairment.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00866308
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