ISSN:
1573-8353
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Methods were developed for the synthesis of 2-ethoxy-1,4-butanediol and 2-ethoxy-1,4-pentanediol. The latter was a mixture of diastereomers. These diols were used to synthesize 5-ethoxy-1,3-dioxepan and 2,2,4-trimethyl-6-ethoxy-1,3-dioxepan. Gas-liquid chromatography was used to demonstrate that 2,2,4-trimethyl-6-ethoxy-1,3-dioxepan is a mixture of cis and trans isomers; the ratio of these isomers is similar to the ratio of diastereomers in the starting 2-ethoxy-1,4-pentanediol. The configurations of the indicated isomers were evaluated by conformational analysis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00478476
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