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  • 1
    Electronic Resource
    Electronic Resource
    Giant Leiomyosarcoma of the Remnant Stomach: Report of a Case (1998)
    Springer
    Surgery today 28 (1998), S. 1056-1060 
    Details
    ISSN: 1436-2813
    Keywords: Key Words: leiomyosarcoma ; gastric remnant ; liver metastasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005950050281
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  • 2
    Electronic Resource
    Electronic Resource
    Giant leiomyosarcoma of the remnant stomach: Report of a case (1998)
    Springer
    Surgery today 28 (1998), S. 1056-1060 
    Details
    ISSN: 1436-2813
    Keywords: leiomyosarcoma ; gastric remnant ; liver metastasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe herein the case of a 73-year-old woman who developed a giant leiomyosarcoma in the remnant stomach 4 years after undergoing a distal gastrectomy for gastric carcinoma. Abdominal ultrasonography and computed tomography revealed a huge tumor, 22 cm in maximum diameter, in the left hypochondrial region. Selective abdominal angiography showed a hypervascular tumor fed by the branches of the splenic artery and left inferior phrenic artery. The tumor arose from the posterior wall of the remnant stomach, and demonstrated marked extragastric growth and direct invasion of the pancreas, transverse colon, and diaphragm on the left side. Total resection of the remnant stomach with en bloc resection of these adjacent organs was subsequently carried out. We reviewed the Japanese literature on this extremely rare tumor and evaluated its clinical profile. In comparison with leiomyosarcoma of the unresected stomach, that of the remnant stomach more frequently showed endogastric-type growth and was accompanied by ulceration of the gastric mucosa. The prognosis of patients with leiomyosarcoma of the remnant stomach appears to be gratly affected by the presence of liver metastases and the tumor diameter, similar to that of patients with leiomyosarcoma of the unresected stomach.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02483961
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  • 3
    Electronic Resource
    Electronic Resource
    Successful Surgical Treatment for Implanted Intraperitoneal Metastases of Ruptured Small Hepatocellular Carcinoma: Report of a Case (1999)
    Springer
    Surgery today 29 (1999), S. 453-457 
    Details
    ISSN: 1436-2813
    Keywords: Key Words: ruptured hepatocellular carcinoma ; implanted intraperitoneal metastases ; small hepatocellular carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005950050442
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Triple carcinomas of the biliary tract associated with congenital choledochal dilatation and pancreaticobiliary maljunction (2000)
    Springer
    Journal of gastroenterology 35 (2000), S. 465-471 
    Details
    ISSN: 1435-5922
    Keywords: Key words: congenital choledochal dilatation ; pancreaticobiliary maljunction ; triple biliary carcinomas
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: We report a rare case of triple carcinomas of the biliary tract associated with congenital choledochal dilatation (CCD) and pancreaticobiliary maljunction (PBM). The patient was a 58-year-old Japanese man who complained of epigastralgia. Ultrasonography and computed tomography revealed an elevated lesion inside the markedly dilated extrahepatic bile duct, thickening of the gallbladder wall, and small polypoid lesions in the gallbladder. Magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography showed CCD and PBM. With a diagnosis of carcinoma of the bile duct and cholesterol polyps in the gallbladder, pylorus-preserving pancreaticoduodenectomy was performed. The resected specimen showed two elevated lesions in the dilated bile duct, cholesterol polyps, and an area of irregular mucosa in the gallbladder. Histopathological examination showed two carcinomas in the bile duct, an adenosquamous cell carcinoma, and a moderately differentiated tubular adenocarcinoma, and a well differentiated tubular adenocarcinoma of the gallbladder. Two years and 6 months after the operation, a solitary metastatic liver tumor was detected. Left hepatic lobectomy was performed. At present, 7 months after the second operation, the patient is doing well with no signs of recurrence. Multiple carcinomas in the biliary tract associated with CCD and PBM, including the details in the present patient, were reviewed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005350070093
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  • 5
    Electronic Resource
    Electronic Resource
    Hepatocellular carcinoma associated with anabolic steroid therapy: Report of a case and review of the Japanese literature (1996)
    Springer
    Journal of gastroenterology 31 (1996), S. 450-454 
    Details
    ISSN: 1435-5922
    Keywords: anabolic steroids ; hepatocellular carcinoma ; aplastic anemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report herein the case of a 35-year-old woman with aplastic anemia who developed hepatocellular carcinoma after long-term therapy with oxymetholone. She was treated with 60mg/day of oxymetholone for 3 years (total dose 64.8g). Alphafetoprotein, hepatitis B surface antigen, and hepatitis C antibody were all negative, but serum titers of carcinoembryonic antigen and carbohydrate antigen were elevated. Lateral segmentectomy of the liver was performed. The histopathological findings were compatible with those of multiple hepatocellular carcinoma without liver cirrhosis. Three years since the operation, the patient is doing well and no signs of tumor recurrence have been detected. According to our review of Japanese cases of hepatocellular carcinoma associated with anabolic steroid therapy, in all instances the tumors developed after long-term administration of anabolic steroids for hematologic diseases. In patients under long-term anabolic steroid therapy, routine screening of the liver by ultrasonography and computed tomography should be performed to detect liver tumors in the early stages.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02355039
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  • 6
    Electronic Resource
    Electronic Resource
    Successful surgical treatment for implanted intraperitoneal metastases of ruptured small hepatocellular carcinoma: Report of a case (1999)
    Springer
    Surgery today 29 (1999), S. 453-457 
    Details
    ISSN: 1436-2813
    Keywords: ruptured hepatocellular carcinoma ; implanted intraperitoneal metastases ; small hepatocellular carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report herein the case of a 53-year-old man with disseminated intraperitoneal metastases caused by the rupture of small hepatocellular carcinoma (HCC). He was admitted to our hospital in shock after suffering a trauma injury to the upper abdomen. Ultrasonography revealed a massive hemoperitoneum. At surgery, 4000 ml of blood was drained from the abdominal cavity and a ruptured tumor, 2 cm in diameter, was found in the right lobe of the liver. The tumor was resected with an adequate surgical margin and subsequent microscopic examination confirmed a diagnosis of moderately differentiated HCC without associated liver cirrhosis. The patient was readmitted 14 months later, following the development of right lower quadrant pain. Ultrasonography and computed tomography revealed extrahepatic abdominal tumors, and abdominal angiography demonstrated four intraperitoneal tumors. At surgery, four implanted metastases adhered to the greater omentum were found and resected. No other tumors were detected. Microscopically, all four tumors were confirmed as moderately differentiated hepatocellular carcinoma. Ruptured HCC may lead to implanted intraperitoneal metastasis, but rupture of small HCC is very rare. While hepatic resection is the treatment of choice for ruptured HCC, according to our review of the literature, only a few patients have survied long-term after resection of implanted metastasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02483040
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  • 7
    Electronic Resource
    Electronic Resource
    Solid Cystic Tumor of the Pancreas in Elderly Men: Report of a Case (1999)
    Springer
    Surgery today 29 (1999), S. 1264-1267 
    Details
    ISSN: 1436-2813
    Keywords: Key Words: solid cystic tumor ; elderly ; malignant potential
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005950050582
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  • 8
    Electronic Resource
    Electronic Resource
    Solid cystic tumor of the pancreas in elderly men: Report of a case (1999)
    Springer
    Surgery today 29 (1999), S. 1264-1267 
    Details
    ISSN: 1436-2813
    Keywords: solid cystic tumor ; elderly ; malignant potential
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Solid cystic tumor of the pancreas is a primary pancreatic neoplasm of unknown etiology that most commonly occurs in young women and ordinarily contains hemorrhagic tissue. We report herein the unusual case of a 75-year-old man found to have a solid cystic tumor in the body and tail of the pancreas, who is the oldest such male patient to be documented in Japan. The results of laboratory data and imaging studies indicated that the patient had a nonfunctioning islet tumor or solid cystic tumor of the pancreas, and distal pancreatectomy with splenectomy was performed. The diagnosis of solid cystic tumor was confirmed based on macroscopic and histological findings of the resected pancreatic tumor. The patient is currently in good health, without any signs of tumor recurrence 1 year, and 4 months after his operation. A total of 181 cases of solid cystic tumors, of the pancreas reported in the Japanese literature, including our case, were reviewed to evaluate the clinical differences between patients aged 50 years or over and those younger than 50 years.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02482220
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  • 9
    Electronic Resource
    Electronic Resource
    Differential expression of tenascin-C and tenascin-X in human astrocytomas (1997)
    Springer
    Acta neuropathologica 93 (1997), S. 431-437 
    Details
    ISSN: 1432-0533
    Keywords: Key words Astrocytoma ; Tenascin-C ; Tenascin-X ; Cell proliferation ; Neovascularization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Tenascins (TNs) are a family of extracellular matrix glycoproteins. The first member of this family to be recognized, tenascin-C (TN-C), is known to be expressed in various tumors including human astrocytomas. Tenascin-X (TN-X) is the latest member of the TN family to be reported, and its expression in tumor tissues has not yet been examined. In this study, we found expression of TN-X in glioma cell lines and human astrocytomas by immunoblot analysis using anti-mouse TN-X antibodies. We also examined the expression of TN-C and TN-X immunohistochemically in a series of 32 human astrocytomas and tissue from 5 normal brains. Expression of TN-X was up-regulated to a higher degree in low-grade astrocytomas than in high-grade astrocytomas. TN-X was mainly localized in the perivascular stroma around tumor vessels, and weakly expressed in the intercellular spaces among tumor cells. In contrast, TN-C was more strongly expressed in the intercellular spaces and in tumor vessels in high-grade astrocytomas (anaplastic astrocytomas and glioblastomas) than in low-grade astrocytomas. In the tissues expressing both TNs, the distribution of TN-X was often reciprocal to that of TN-C. These findings indicate that the expression of TN-C and TN-X in astrocytomas is different, and that these glycoproteins could be involved in neovascularization in different manners.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010050636
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