ISSN:
1420-9071
Keywords:
Ecdysone
;
20-hydroxyecdysone
;
ticks
;
salivary gland degeneration
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Following engorgement, female ixodid ticks secrete a ‘tick salivary gland degeneration factor’ (TSGDF) into the hemolymph. Here we show that the arthropod ecdysteroid hormones, ecdysome and 20-hydroxyecdysone, induce degeneration of tick salivary glands maintained in organ culture. The effective dose range in vitro is 30–300 ng/ml, a range reported to be physiological for this species following repletion. In addition, infusion of 20-hydroxyecdysome in vivo induces salivary gland degeneration. We therefore propose that TSGDF may be an ecdysteroid.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02012574
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