ISSN:
1432-119X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary N-acethylserotonin, the substrate of hydroxy-indol-o-methyl-transferase (HIOMT) is being synthetized by the serotonin-acethyl-transferase. The localization of the enzyme in the pineal gland has been studied by uranyl and copper ferrocyanide methods. Both methods revealed a mitochondrial localization. The reaction precipitate was situated on the outer and inner membrane as well as in the inner compartment of the mitochondrium. Without acethyl-Co A the reaction failed to take place. Copper ferrocyanide was found more favourable than the uranyl ferrocyanide. No specific reaction, extramitochondrial precipitate occured.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02463562
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