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  • 1
    Electronic Resource
    Electronic Resource
    HEART RATE RESPONSES TO AUDITORY CLICKS IN NEONATES (1971)
    Oxford, UK : Blackwell Publishing Ltd
    Psychophysiology 8 (1971), S. 0 
    Details
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: The neonatal heart rate (HR) response to brief stimuli has generally been reported to be a monophasic acceleration. In this study brief auditory clicks to 6 neonates elicited, to a significantly greater degree than in non-stimulus conditions: 1) deceleration alone, 2) acceleration alone, and 3) a biphasic response consisting of an initial deceleration and a subsequent acceleration.The data are not yet available which would permit selection among the orienting reflex (OR), defense reflex, startle reflex, and Moro reflex models of these HR responses. With regard to peripheral mechanism, the early decelerative response was probably mediated by increased vagal inhibitory tone. The later accelerative response may have been mediated by one or more of the following mechanisms: decreased vagal inhibitory tone, activation of vagal accelerator fibers, and/or activation of sympathetic accelerator fibers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1469-8986.1971.tb00448.x
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  • 2
    Electronic Resource
    Electronic Resource
    Introduction and Overview (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 568 (1989), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1989.tb12485.x
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  • 3
    Electronic Resource
    Electronic Resource
    Preface (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 747 (1994), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1994.tb44397.x
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  • 4
    Electronic Resource
    Electronic Resource
    Preface (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 802 (1996), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1996.tb32591.x
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  • 5
    Electronic Resource
    Electronic Resource
    Involvement of both cholinergic and catecholaminergic pathways in the central action of methylphenidate: A study utilizing lead-exposed rats (1977)
    Springer
    Psychopharmacology 55 (1977), S. 187-193 
    Details
    ISSN: 1432-2072
    Keywords: Methylphenidate ; Lead toxicity ; Cholinergic and catecholaminergic effects ; Mesencephalic reticular formation ; CNS ; Hyperkinesis ; Supersensitivity ; Oxotremorine ; Nicotine ; Model
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of methylphenidate (MPH) and the cholinergic agonists nicotine and oxotremorine were tested on the spontaneous multiple unit activity in the mesencephalic reticular formation of two groups of rats. In control rats i.v. MPH (1 mg/kg), nicotine (0.125 mg/kg), and oxotremorine (0.5 mg/kg) all attenuated the unit activity with latencies of less than 10 min. In another group of rats, exposed to lead acetate since birth, the extent of attenuation of unit activity induced by MPH and nicotine was reduced and the latency of effect was delayed by 45–50 min. The latency of the oxotremorine effect was not changed but the attenuation of unit activity was more pronounced in the lead-treated group. Pretreatment with spiroperidol, to inhibit the aminergic receptors, diminished the inhibitory effect of MPH in the control group but not in the lead-treated group, whereas the attenuating effect of oxotremorine was not affected in either group. These data support our previous evidence that MPH exerts its action in the central nervous system by a cholinergic pathway in addition to published catecholaminergic pathways. Furthermore, the present findings indicate that chronic leadexposure in rats results in cholinergic hypofunction and supersensitivity at central cholinergic receptor sites. This alteration of central cholinergic function may be partially attributed to the malnutrition observed in the lead-exposed animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01457857
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  • 6
    Electronic Resource
    Electronic Resource
    Differential effects of methylphenidate on reticular formation and thalamic neuronal activity (1975)
    Springer
    Psychopharmacology 44 (1975), S. 11-15 
    Details
    ISSN: 1432-2072
    Keywords: Methylphenidate ; Hyperkinesis ; Mesencephalic Reticular Formation ; Thalamus ; Attention ; Arousal ; CNS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Intravenous administration of methylphenidate (1 or 2 mg/kg) markedly attenuated the unit discharge rate in the mesencephalic reticular formation of rats and cats. Concurrently this drug enhanced the neural activity in the primary sensory nuclei of the thalamus. The differential effects of methylphenidate on these two neural systems suggest a possible mechanism by which it may improve attentive processes in hyperkinesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00421176
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    Paper (German National Licenses)
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