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  • 1
    Electronic Resource
    Electronic Resource
    Diterpenes from Olearia Species (1988)
    s.l. : American Chemical Society
    Journal of natural products 51 (1988), S. 513-516 
    Details
    ISSN: 1520-6025
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/np50057a010
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  • 2
    Electronic Resource
    Electronic Resource
    New Sesquiterpene Lactone Type from Dugaldia hoopesii (1984)
    s.l. : American Chemical Society
    Journal of natural products 47 (1984), S. 658-662 
    Details
    ISSN: 1520-6025
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/np50034a015
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  • 3
    Electronic Resource
    Electronic Resource
    A Versatile High-Resolution Spectrofluorometer (1961)
    s.l. : American Chemical Society
    Analytical chemistry 33 (1961), S. 1362-1365 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60178a025
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  • 4
    Electronic Resource
    Electronic Resource
    Correction for Anomalous Fluorescence Peaks Caused by Grating Transmission Characteristics. (1963)
    s.l. : American Chemical Society
    Analytical chemistry 35 (1963), S. 1099-1100 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60201a059
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  • 5
    Electronic Resource
    Electronic Resource
    Computer acquisition and analysis of gas chromatographic data (1972)
    s.l. : American Chemical Society
    Analytical chemistry 44 (1972), S. 1961-1971 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60320a019
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  • 6
    Electronic Resource
    Electronic Resource
    Presentation of allergen in different food preparations affects the nature of the allergic reaction – a case series (2003)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 33 (2003), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Characterization of fatal and non-fatal reactions to food indicates that the majority of reactions are due to the ingestion of prepared foods rather than the non-processed allergen. In an ongoing study that used a double-blind placebo-controlled food challenge to investigate peanut allergy and clinical symptoms, the observed reaction severity in four of the first six subjects was greater than anticipated. We hypothesized that this was due to differences in the composition of the challenge vehicle.Objective The aim was to investigate whether the severity of observed challenge reactions would be repeated on re-challenge with a lower fat challenge vehicle.Methods Peanut-allergic subjects were re-challenged with a lower fat recipe after reacting more severely than was anticipated to an initial peanut challenge. Similar challenge vehicle recipes were used, the only difference being the lower fat content (22.9% compared with 31.5%). The peanut content of the two recipes was analysed using RAST inhibition studies and ELISA tests.Results Three of four subjects reacted to much smaller doses of peanut protein on re-challenge (mean dose equivalence – 23 times less peanut) with the lower fat recipe. RAST inhibition showed that neither recipe altered epitope recognition. The higher fat recipe required twice as much peanut to cause 50% inhibition. ELISA detected far lower levels of peanut in the higher fat recipe (220 000 parts per million (p.p.m.)) than in the lower fat recipe (990 000 p.p.m.).Conclusion The fat content of a challenge vehicle has a profound effect on the reaction experienced after allergen ingestion. This is another factor to be considered in assessing the risk of certain foods to food-allergic consumers and adds another dimension to clinical, research and regulatory practice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2222.2003.01795.x
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  • 7
    Electronic Resource
    Electronic Resource
    Does severity of low-dose, double-blind, placebo-controlled food challenges reflect severity of allergic reactions to peanut in the community? (2005)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 35 (2005), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background The severity of allergic reactions to food appears to be affected by many interacting factors. It is uncertain whether challenge-based reactions reflect the severity of past reactions or can predict future risk.Objective To explore the relationship of a subject's clinical history of past reactions to the severity of reaction elicited by a low-dose, double-blind, placebo-controlled food challenge (DBPCFC) with peanut.Method Cross-sectional questionnaire assessment of community-based allergic reactions and low-dose DBPCFC in self-selected peanut-allergic subjects. Reaction severity was assessed using a novel scoring system, taking account of the dose of allergen ingested.Results Forty subjects (15 males, 23 children, 23 asthmatics by history) were studied. Only the most recent community reaction predicted the severity of reaction in the DBPCFC, but even this association was weak (r=0.37, P=0.03). Peanut-specific IgE (PsIgE) and skin prick test (SPT) weal size were not associated with community score but PsIgE level correlated well with the challenge score (r=0.6, P=0.001). Asthma did not affect the eliciting dose or challenge score directly but the association of PsIgE and challenge score was stronger in those without asthma (r=0.72, P=0.001) than in those with asthma (r=0.48, P=0.02).Conclusions The scoring system developed appears to improve the sensitivity of assessment of reactions induced by DBPCFC. This is the first prospective study showing an association between PsIgE levels and clinical reactivity in DBPCFC, an effect that is more pronounced in non-asthmatics. This finding has important implications for the clinical care of subjects with food allergy. There is a poor correlation between the severity of reported reactions in the community and the severity of reaction elicited during low-dose DBPCFC with peanut.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.2005.02312.x
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  • 8
    Electronic Resource
    Electronic Resource
    Oxidation and thermal annealing effects on native and ion-irradiated PbTe films grown by molecular beam deposition (1985)
    Springer
    Applied physics 37 (1985), S. 145-151 
    Details
    ISSN: 1432-0630
    Keywords: 61.80.Jh ; 73.60.Fw ; 82.65−i
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Investigations are reported into the effect of low-pressure oxygen exposure and thermal annealing on the carrier transport properties of native and 350 eV Ar+ bombarded PbTe films. The electrical measurements were madein situ on MBD-grown PbTe films without breaking vacuum. On native surfaces, oxidation was initially sustained by diffusion of a donor species from the film bulk to the surface, where reaction with oxygen occured. This diffusion process was apparently inhibited on ion irradiated films and direct doping of the film surface effected a gradual reduction in the ion-induced electron accumulation resident at the film surface. The native properties and behavioural characteristics of the films could be recovered by thermal annealing of the ion-irradiated and/or oxidized films at 300–350 °C.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00617499
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  • 9
    Electronic Resource
    Electronic Resource
    Oxygen and monatomic hydrogen interactions with PbTe film surfaces prepared by molecular-beam deposition (1986)
    Springer
    Applied physics 40 (1986), S. 7-12 
    Details
    ISSN: 1432-0630
    Keywords: 73.60.Fw ; 61.70.Tm ; 82.65-i
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The effects on the electrical properties and surface composition of molecular-beam-deposited PbTe films to exposure by oxygen and monatomic hydrogen were investigated. Three stages of oxidation have been identified, depending on the pressure regime employed. Characteristic differences in the response of each of the three oxides to thermal annealing, electron irradiation during Auger analysis and to monatomic hydrogen exposure were observed. The kinetics of n-type doping by monatomic hydrogen, and its reversibility under ultra-high vacuum and oxygen-exposure conditions are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00616585
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  • 10
    Electronic Resource
    Electronic Resource
    Sources of variability in laboratory weathering (1970)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 10 (1970), S. 309-313 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A statistical study was conducted to determine the significance of the sources of variability in the laboratory (carbon arc) weathering of a light-stabilized polyester resin system. Color fastness of the resin was evaluated in terms of changes in total color, lightness, and chromaticity. Factors that significantly influenced the results were variability within castings and between batches of resin, location of the specimen within the exposure apparatus, and the storage time prior to testing. The carbon arc instrument provided a relatively insensitive test for evaluating a light-stabilized polymer system, chiefly because, with a stable polymer, small random variations in response become almost equal to the small change in color developed on exposure.
    Additional Material: 7 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760100510
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