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  • 1
    Electronic Resource
    Electronic Resource
    IgA in Blood and Thoracic Duct Lymph: Concentration and Degree of Polymerization (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 7 (1978), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Lymph fluid and serum samples from four mammalian species were studied for the concentration and degree of polymerization of IgA. The results suggest that in the mouse, in the rat and in the dog circulating IgA represents only a small fraction of all IgA entering the blood stream from the lymph vessels. A majority of the input IgA of Oligomeric type (13S, 11S and 9S) in these species is cleared rapidly. Monomeric IgA. and in the mouse and the dog the dimeric (9S) variety, dwell much longer in the blood, and because of this they form the majority of the circulating IgA. Blood concentration of IgA is high in man, a species whose blood seems to receive mostly monomeric IgA. it is much lower in the rat. mouse and dog, and in those species most of IgA entering the blood is probably oligomeric.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3083.1978.tb00448.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Determination of IgG subclass antibodies against wheat flour antigens by an ELISA technique (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 44 (1989), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We describe the assay conditions for an enzyme-linked immunoassay for the determination of IgG and IgG subclass antibodies in serum to water-soluble wheat flour antigens. The optimal antigen coating concentration was 5 μg/ml for total IgG, IgG1, IgG4 and 100 μg/ml for IgG2. Serial dilutions of test sera were used and commercially available monoclonal mouse anti-human IgG isotype antibodies (as ascites fluid) were diluted 1:500–1:1000. Specific wheat flour antibodies belonging to the IgG1, IgG2 and IgG4 subclasses were detected. Despite the lack of standardized isotype-specific second mouse monoclonal antibodies, the subclass antibody levels between flour-exposed bakers and controls could be compared. We observed significantly higher IgG1, IgG2 and IgG4 subclass antibodies among 23 bakers than among 12 non-exposed controls, but no IgG3 antibodies were detected. The differences in biological activities of the IgG subclass antibodies may explain the clinical and pathophysiological features for flour-induced occupational allergic diseases among bakers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1989.tb04173.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Immunohistochemical identification of renal lysozyme during allograft rejection in man (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 3 (1979), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An immunoperoxidase staining method was used to identify lysozyme in biopsy or transplantectomy specimens of human renal allografts during reversible and irreversible rejection of the grafts. Proximal tubules in apparently functioning nephrons showed lysozyme staining. In irreversibly rejected grafts, infiltrating mononuclear phagocytes in and near peritubular and glomerular capillaries also stained intensely for lysozyme. In acute necrotizing arteritis, lysozyme-positive cells (mononuclear phagocytes) infiltrated the blood vessel wall. The presence of infiltrating lysozyme-positive cells in the transplant was consistent with poor graft survival.The variation in lysozyme staining of proximal tubular cells apparently was a reflection of the differences in the reabsorption capacity of the tubular cells, attributable to the tubular dysfunction of renal allografts. The infiltrating lysozyme-positive cells probably contribute to the increased urinary excretion of lysozyme during acute rejection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1979.tb03024.x
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  • 4
    Electronic Resource
    Electronic Resource
    Effects of Lysozyme on Normal and Transformed Mammalian Cells (1973)
    [s.l.] : Nature Publishing Group
    Nature 243 (1973), S. 331-335 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Homologous mammalian lysozymes have specific effects on the in vitro growth patterns and morphology of normal and transformed mammalian cells, apparently due to effects on constituent membranes. Lysozyme may be important in the surveillance of membranes and may be a mediator of the antitumour ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/243331a0
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Lysozyme content of tears in normal subjects and in patients with external eye infections (1983)
    Springer
    Graefe's archive for clinical and experimental ophthalmology 221 (1983), S. 86-88 
    Details
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied the lysozyme content of tears in 267 subjects (521 eyes), including 241 healthy subjects, 7 patients (14 eyes) with bilateral blepharitis, 8 patients (12 eyes) with conjunctivitis, and 11 patients (16 eyes) with keratitis. The concentration of lysozyme in the tears rises with age between childhood and maturity. The highest values were seen in the age group of 21–40 years, and a decrease of lysozyme concentration occurred with an increase in age from 30–40 years. The mean lysozyme content of tears was 1,768 μg/ml in halthy subjects; no significant differences occurred between the sexes. Patients with blepharitis, conjunctivitis, and keratitis had normal mean lysozyme content of tears. The tears of patients with herpes simplex keratitis had low lysozyme values.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02133813
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    Paper (German National Licenses)
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