ISSN:
1432-2072
Keywords:
Thyrotropin releasing hormone
;
Thiobarbiturate
;
Rhesus monkeys
;
Rate of responding
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Similar excitatory or depressant response rate dependent effects on monkeys responding on a variable interval reinforcement schedule were observed following intravenous administration of either thyrotropin releasing hormone (TRH) or thiobarbiturate. However, these agents were mutally antagonistic when given together even though the response rate altering effects of each agent were in the same direction. These findings establish an additional behavioral effect of exogenously administered TRH in primates and suggest that barbiturates might alter behavior in part through an interaction with brain TRH receptive mechanisms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00426819
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