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  • 1
    Electronic Resource
    Electronic Resource
    Application, Feasibility, and Efficacy of a Combined Intravascular Ultrasound and Stent Delivery System: Results from a Prospective Multicenter Trial (2005)
    350 Main Street , Malden , MA 02148-5020 , USA , and P.O. Box 1354, Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Science Inc
    Journal of interventional cardiology 18 (2005), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: Intravascular ultrasound (IVUS) is the reference method for in vivo assessment of vessel dimensions and coronary plaque composition, which can influence device selection as well as stent sizing. Objectives: The objective of this prospective multicenter-study was to test the application, safety, and feasibility of a new combined IVUS and stent delivery system. Methods: A total of 32 patients with planned direct stent implantation under IVUS guidance were included in the study. Procedural as well as angiographical and IVUS characteristics of the stent implantation with the combined IVUS and stent delivery system were assessed and compared to a historical control cohort where IVUS-guided stenting was performed with a separate IVUS catheter. Results: Direct stent placement was successfully performed in all patients and no malfunctions of the system were noted. A postinterventional IVUS assessment was possible in 27 (87%) of the 31 patients. The IVUS information led to a change in therapeutic strategy in 16 (50%) of the 32 patients. In the study group, both the procedural time and the amount of contrast dye were significantly lower than in the historical IVUS-guided stenting control group. A clinical 12-month follow-up revealed a 89% event-free survival and a target vessel revascularization rate of 7%. Conclusion: The use of a combined IVUS and stent delivery device is safe, easy to handle, and can provide helpful additional information to guide a percutaneous coronary interventions procedure. Beyond angiography, these informations had significant impact on the interventional strategy in these patients, which resulted in a low rate of major adverse cardiac events. The concept of combining IVUS information and a stent delivery system may be increasingly attractive with evolving imaging modalities like virtual histology or a combination with drug-eluting stents.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8183.2005.00075.x
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  • 2
    Electronic Resource
    Electronic Resource
    Reduction of Pacing Output Coupling Capacitance for Sensing the Evoked Response (2001)
    Oxford, UK : Blackwell Futura Publishing, Inc.
    Pacing and clinical electrophysiology 24 (2001), S. 0 
    Details
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: SPERZEL, J., et al.: Reduction of Pacing Output Coupling Capacitance for Sensing the Evoked Response. Sensing of the intracardiac evoked response (ER) after a pacing stimulus has been used in implantable pacemakers for automatic verification of capture. Reliable detection of ER is hampered by large residual afterpotentials associated with pacing stimuli. This led to the development of various technological solutions, like the use of triphasic pacing pulses and low polarizing electrode systems. This study investigated the effect of reducing the coupling capacitance (CC) in the pacemaker output circuitry on the magnitude of afterpotential, and the ability to automate detection of ventricular evoked response. A CC of 2.2 μF and four different blanking and recharge time settings were clinically tested to evaluate its impact on sensing of the ventricular ER and pacing threshold. Using an automatic step-down threshold algorithm, 54 consecutive patients, aged 70 ± 10 years with acutely (n = 27) or chronically (n = 27) implanted ventricular pacing leads were enrolled for measurement testing. Routine measurements, using a standard pacing system analyzer (PSA), were (mean ± SD) impedance 569 ± 155 Ω, R wave amplitude baseline to peak 9.8 ± 3.7 mV and threshold 0.9 ± 0.7 V at 0.4-ms pulse width. This new capture verification scheme, based on a CC of 2.2 μF and recharge/blanking timing setting of 10/12 ms, was successful in 52 patients which is equivalent to a success rate of 96%. In a subgroup of 26 patients implanted with bipolar ventricular leads (10 chronic, 16 acute), data were collected in unipolar (UP) and bipolar (BP) pace/sense configurations. Also, ER signals were recorded with two different band-pass filters: a wider band (WB) of 6–250 Hz and a conventional narrow band (NB) of 20–100Hz. WB sensing from UP lead configuration yielded statistically significant larger signal to artifact ratios (SAR) than the other settings (P 〈 0.01). A dedicated unipolar ER sensing configuration using a small output capacitor and a wider band-pass filter enables adequate automatic capture verification, without any restrictions on pacing lead models or pacing/sensing configurations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-9592.2001.01377.x
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  • 3
    Electronic Resource
    Electronic Resource
    Evaluation of Fusion Beat Detection with a New Ventricular Automatic Capture Algorithm in ICDs (2005)
    350 Main Street , Malden , MA 02148-5018 , USA and 9600 Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Science Inc
    Pacing and clinical electrophysiology 28 (2005), S. 0 
    Details
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study evaluated a newly developed automatic capture verification scheme for implantable cardioverter defibrillators (ICDs) regarding discrimination of capture, fusion, and noncapture beats, with an emphasis on fusion detection. The algorithm uses evoked response detection based on a sensing vector from right ventricular shocking coil to Can. Patients undergoing ICD implant or replacement were enrolled in this study. An external system was used for pacing and data acquisition. To provoke ventricular fusion beats, VVI patients were paced close to the rate of their intrinsic rhythm and DDD patients were paced close at their intrinsic PR interval. Surface ECG and wideband filtered intracardiac electrograms were recorded for off-line analysis. Each paced beat was independently classified visually by surface ECG and by the automatic detection algorithm. The algorithm performance was then evaluated by comparing the classification results. Twenty-seven patients (22 males, 5 females; 63.8 ± 12.5 years) were analyzed. Device and lead demographics were: 18 DDD/9 VVI; 16 dedicated bipolar, 11 integrated bipolar leads; 18 acute, 9 chronic (3.7 ± 2.0 years) leads. In total, 2064 beats were analyzed, including 1,477 fusion beats and 587 capture beats. Fusion detection sensitivity and specificity were 99.5% and 99.0%, respectively. Seven true-fusion beats (0.5%) were classified as capture and 6 capture beats (1.0%) were identified as fusions. Capture or fusion beats were never detected as non-capture beats. It is concluded that the algorithm was effective in detecting fusion beats. It could potentially be used in ICD applications that need accurate fusion detection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8159.2005.00027.x
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  • 4
    Electronic Resource
    Electronic Resource
    When females should contest for food – testing hypotheses about resource density, distribution, size, and quality with Hanuman langurs (Presbytis entellus) (1998)
    Springer
    Behavioral ecology and sociobiology 42 (1998), S. 225-237 
    Details
    ISSN: 1432-0762
    Keywords: Key wordsPresbytis entellus ; Resource use ; Resource distribution ; Resource quality ; Feeding competition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Predictions of ecological models on female social relationships (van Schaik 1989) and their links with food distribution and the potential competitive regime are used to analyze the feeding and spatial behavior, and resource density, size, distribution, and quality in a forest population of Hanuman langurs (Presbytis entellus). In contrast to other populations, and assumptions on folivorous primates, the females of this population exhibit a linear dominance hierarchy. The langurs concentrated their feeding on three key resources with a low density and clumped distribution. Two out of the three key resources contained significantly higher levels of extractable protein and soluble sugar than other food plants, indicating high spatial variability of food quality. Even the mature leaves of the most preferred food plant were about twice as nutritious as those from other food plants. Group spread was small and only a single high-quality resource was used at a time. Finally, even rich resources could accommodate only a subset of a group. These findings fit predictions made for the prevalence of within-group contest competition. Given the observed food distribution and phytochemical heterogeneity of mature foliage, even females of folivorous species should contest for food. The effect of female dominance rank on size and composition of feeding parties also agrees with this prediction. A comparison with data from another forest population, where female dominance relations are weakly developed, revealed a clear-cut difference in the use and abundance of resources. It is argued that between-population differences in female social relationships within a species may be viewed as adaptive responses to local habitat conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002650050434
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  • 5
    Electronic Resource
    Electronic Resource
    Long-term study of infant-carrying behavior in captive common marmosets (Callithrix jacchus): Effect of nonreproductive helpers on the parents' carrying performance (1993)
    Springer
    International journal of primatology 14 (1993), S. 79-93 
    Details
    ISSN: 1573-8604
    Keywords: common marmoset ; infant-carrying ; effect of helpers ; laboratory environment ; long-term study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Infant-carrying behavior in four families ofCallithrix jacchus was investigated over a period covering six to eight litters. We evaluated the effect of the total number of helpers and the number of adult helpers on the parents' carrying performance for the total carrying period and for three age stages of the infants. The carrying performance of the parents reached an asymptote beginning with litters 3 to 5. In two groups, the carrying performance of the parents was significantly negatively correlated with group size. However, considerable differences existed within each group and between the groups. The mother was the primary caregiver in the early weeks of the infants' lives. In this phase the helpers' contribution to carrying was less than might be expected. The relief of the parents from infant-carrying was greatest when the infants were 4 to 7 weeks old. Breeding males benefited most and from every helper, while breeding females benefited most from adult helpers, i.e., the carrying performance of the breeding female was considerably reduced until the respective group had grown to 8 to 10 members (infants not included). This group size is considered to be ideal for maximal relief of the parents from infant carrying. An increasing number of adult nonreproductive helpers (〉4 or 5) does not induce a further reduction of the parents' carrying performance. Infant-rearing experience of nonreproductive helpers seems to be more important for the parents' and, especially, the breeding female's relief from infant-carrying than the overall number of helpers is. The data also strongly evidence that a group member's participation in infant-carrying is influenced by housing conditions and the demographic history of the group.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02196504
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  • 6
    Electronic Resource
    Electronic Resource
    Effects of familiarity on the behaviour towards intruders in captive common marmosets (Callithrix jacchus) (1994)
    Springer
    Primates 35 (1994), S. 89-93 
    Details
    ISSN: 0032-8332
    Keywords: Callithrix jacchus ; Intruder study ; Familiarity ; Defending behaviour ; Immigration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A study on the behaviour of a group of common marmosets (Callithrix jacchus) towards unrelated intruding conspecifics (juvenile male twins) was performed. The group members' proximity to the intruders during two consecutive study periods was analyzed. During the first period in which the experimental conditions as well as the intruders were unfamiliar, all but one group member were equally likely to stay near the intruders and usually more than three individuals were present simultaneously. During the second period the group members showed different scores of proximity towards the intruders. One individual, an adult male, was in close proximity nearly the whole time. Additionally, the number of individuals simultaneously staying near the intruders was clearly reduced. It is argued that (1) the change in behaviour of the group members was affected by the increasing familiarity and (2) intruder experiments with unfamiliar conspecifics are only of partial value for clarification of the process of immigration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02381489
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  • 7
    Electronic Resource
    Electronic Resource
    Beiträge zur Kenntnis der Oxydhydrate. XXXII. Das System Vanadinpentoxyd/Wasser (1930)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 193 (1930), S. 81-92 
    Details
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19301930108
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  • 8
    Electronic Resource
    Electronic Resource
    Beiträge zur Kenntnis der Oxydhydrate. XXXIV. Das System Tantalpentoxyd/Wasser (1930)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 193 (1930), S. 100-105 
    Details
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19301930110
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  • 9
    Electronic Resource
    Electronic Resource
    Beiträge zur Kenntnis der Oxydhydrate. XXXIII. Das System Niobpentoxyd/Wasser (1930)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 193 (1930), S. 93-99 
    Details
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19301930109
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    Paper (German National Licenses)
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