ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] Soluble TNF-a is released by cleavage of the precursor at the Ala76-Val77 bond, and we have previously shown that TACE cleaves a 12-residue peptide spanning this site with the same specificity3'11. The enzyme was purified by following its activity with an assay for cleavage of this processing-site ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/385729a0
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