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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 311 (1969), S. 148-158 
    ISSN: 1432-2013
    Keywords: Decerebrate State ; Extensor Motoneurones ; Recurrent Inhibition ; Disinhibition ; Schlüsselwörter ; Dezerebrierungsstarre ; Extensor-Motoneurone ; Recurrente Inhibition ; Disinhibition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Trotz kontinuierlicher Anaesthesie und Unterbrechung der Gamma-Spindelschleife löst die natürliche oder elektrische Reizung homonymer Ia-Afferenzen mit konstanter Stärke nach intercolliculärer Dezerebrierung an Extensor-Motoneuronen regelmäßigere Antworten, Verkürzung der Reflexzeit, Zunahme der Entladungsfrequenz, Verstärkung der post-tetanischen Potenzierung und Rekrutierung aus. Da der Grad der recurrenten Hemmung abnimmt, schließen wir, daß die gesteigerte Erregbarkeit der Extensor-Motoneurone im Zustand der Dezerebrierung mit Disinhibition verbunden ist. Die mit einem konstanten Quantum reflexwirksamer Afferenzen erhaltenen Resultate sprechen für unsere Annahme, daß Spastizität nicht hauptsächlich auf fusimotorischer Enthemmung beruht.
    Notes: Summary Even with continued anesthesia and interrupted gamma-loop intercollicular decerebration leads in extensor motoneurones (excited by electrical or natural stimulation of homonymous Ia-afferents with constant strength) to the following phenomona: more regular responses, shortening of reflex time, increase of discharge frequency, enhancement of post-tetanic potentiation, and recruitment. Because the degree of recurrent inhibition is diminished we conclude that the higher excitability of extensor motoneurones in the decerebrate state is correlated with disinhibition. Furthermore the results obtained with the afferent input for motoneurones kept constant favour our assumption that spasticity is not based merely on the release of fusimotor activity.
    Type of Medium: Electronic Resource
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