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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Cancer Genetics and Cytogenetics 18 (1985), S. 283-293 
    ISSN: 0165-4608
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International journal of clinical oncology 4 (1999), S. 384-389 
    ISSN: 1437-7772
    Keywords: Key words Adenocarcinoma of the uterine cervix ; Ovarian conservation ; Ovarian transposition ; Ovarian recurrence ; Prognosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background. Our study had two aims: (1) to evaluate the effect of ovarian conservation on the prognosis of patients with adenocarcinoma of the cervix and (2) to determine the method by which – and the stage up to which – ovaries can be conserved without adversely affecting a favorable prognosis. Methods. We performed either radical hysterectomy with lymphadenectomy or simple hysterectomy on 70 patients in stages 0 to IIIab of adenocarcinoma of the cervix (International Federation of Gynecology and Obstetrics). The postmenopausal patients underwent oophorectomy, while the ovaries of premenopausal patients were left in situ or transposed laterally. We then followed the subsequent condition of the patients to see whether or not ovarian conservation affected their ability to survive for up to 5 years. Results. We found no evidence of ovarian metastasis among patients in stages 0 to IIab of the disease, while three cases were found in patients whose carcinoma was in stage IIIab; 94% of the patients whose ovaries had been conserved survived for 5 years; of the patients who underwent oophorectomy, 100% survived. However, the difference was not significant. Two patients (stages Ib and IIb) suffered a recurrence of cancer in the transposed ovaries: at the time of the initial surgery the lymph nodes in both patients had been positive. Conclusions. If patients with adenocarcinoma of the cervix are operated on during stages 0 to Ia of the disease, ovarian conservation will not affect survival; ovaries can be left in situ or can be transposed laterally without affecting the survival prognosis.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 70 (1981), S. 33-41 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Morphogenesis of human rotavirus type 2 Wa strain in MA 104 cells was observed. The virus antigen in the cytoplasm was detected by indirect immunofluorescence twelve hours after infection. The cytopathic effect occurred 24 hours after infection when virus particles were detected by EM in the culture fluid as well as in thin sections of the infected cells. Virus particles were observed in the dilated RER, nuclear envelope (perinuclear space), viroplasm, and a lysosome-like body. Three types of virus particles were noted: double-shelled particles 75–85 nm in diameter, single-shelled particles 64–68 nm in diameter and electron-dense nucleoids or cores 32–40 nm in diameter. The outer shell of virus particles was acquired by budding through the membrane of the dilated RER. Tubular structures, similar in diameter to the single-shelled particles, were found in the cytoplasm and nucleus of infected MA 104 cells. Bundles of filaments or the leaflet-like inclusion bodies of membrane-bounded bundles of filaments were found in the cytoplasm and seemed to be associated with virus particles.
    Type of Medium: Electronic Resource
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