ISSN:
1573-8221
Keywords:
Gamma-irradiation
;
adenylate cyclase
;
cyclic AMP phosphodiesterase
;
5′-nucleotidase, rat liver, ontogeny
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Activity of adenylate cyclase (ADCase), cyclic AMP phosphodiesterase (PDE), and 5′-nucleotidase was investigated in plasma membranes from the liver of 20-day rat embryos, either normal or exposed to ionizing radiation. Irradiation of the plasma membranes with gamma-rays in doses of between 0.1 and 100 kR was shown to reduce ADCase activity, and to have a more marked effect, in the case of larger doses, when accompanied by stimulation by isoproterenol. The 5′-nucleotidase and PDE activity was unchanged under the influence of doses up to 100 kR.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00831003
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