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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 192 (1961), S. 629-630 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE sensory side of the nervous system is basically X 'noisy'. Information supplied by sensory stimulation is transmitted through the brain as patterns of nerve impulses. In the absence of stimulation, however, the trains of nerve impulses do not subside completely but are replaced by a ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 177 (1956), S. 888-888 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The capacitance per unit length and asymmetry effects were calculated for a number of other symmetrical cross-sections. These calculations all gave the same value, namely, -5-- e.s.u., as the capacitance per unit length, and this result led one of us (D. G. L.) to propose and prove the following ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 216 (1967), S. 921-922 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1. A, Pen recording showing four asynchronous trains of periodic stimuli, each at a nominal frequency of 100/sec, and the simultaneous discharge in a ventral root filament. Individual stimulus strengths were confined to less than max. Gpl, and adjusted such that simultaneous stimuli processes ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of mathematical biology 12 (1981), S. 153-172 
    ISSN: 1432-1416
    Keywords: Drug receptor interaction ; Stochastic model ; Birth and death processes ; Postsynaptic current noise ; Muscle relaxants ; Competition ; Ionic channel blocking
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract Stochastic modelling of drug receptor interaction at the neuromuscular junction with birth and death processes is presented. Systems with only one drug and two drugs interacting are investigated separately. The total number of receptors is assumed finite and only single receptor binding is considered. It has been possible to obtain exact analytical solutions to forward Kolmogorov equations yielding the transition probability densities and the associated probability generating functions.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 11 (1973), S. 262-267 
    ISSN: 1741-0444
    Keywords: Digital computer ; anaesthesia control ; respiration control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Description / Table of Contents: Sommaire Cet article décrit le contrôle d'un certain nombre de variables physiologiques interactives par un ordinateur on-line fonctionnant en temps réel. Il est démontré qu'un système contrôlé par ordinateur peut, en surveillant les valeurs de la pression artérielle, le pourcentage de CO2 en fin de cycle et le pourcentage de O2 respiré, maintenir la respiration et l'anesthésie d'un animal recevant de l'air dans des tolérances strictes. Sous le contrôle d'un ordinateur, il est possible de compenser les perturbations aléatoires des paramètres du système et l'on peut traiter automatiquement les changements affectant les niveaux désirés des variables.
    Abstract: Zusammenfassung Die Steuerung einer Anzhhl von in Wechselwirkung stehenden physiologischen Variablen durch einen on-line, in real-time arbeitenden Rechner wird vorgeführt. Es wird gezeigt, dass ein komputergesteuertes System durch die Überwachung des arteriellen Blutdruckes, der endzyklischen CO2 Konzentration und der inspirierten O2 Konzentration, die Respiration und d Anaesthesie eines beatmeten Tieres innerhalb enger Toleranzgrenzen erbalten kann. Es ist möglich, unter Rechnerkontrolle statistisch auftretende Störungen der Systemparameter anzukompensieren, und Abweichungen von den gewünschten Werten der Variablen können automatisch berücksichtigt werden.
    Notes: Abstract Control of a number of interactive physiological variables by an online computer, operating in real time, is demonstrated. It is shown that a computer-controlled system, by monitoring values of arterial blood pressure, end-tidal CO2 percentage and inspired O2 percentage, can maintain the respiration and anaesthesia of a ventialted animal within close tolerances. Under computer control, it is possible to compensate for random disturbances of the system parameters, and changes in the desired levels of the variables can be dealt with automatically.
    Type of Medium: Electronic Resource
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