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  • 1
    Electronic Resource
    Electronic Resource
    HLA and testicular cancer (1979)
    [s.l.] : Nature Publishing Group
    Nature 277 (1979), S. 216-217 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The study population consisted of 61 patients from the Uni-versity of Minnesota. Thirty patients had seminoma, 27 had embryonal cell carcinoma, 26 had teratocarcinoma, and 7 patients had choriocarcinoma (some of the patients had mixed tumours). All patients had completed treatment (surgery, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/277216a0
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  • 2
    Electronic Resource
    Electronic Resource
    The percutaneous removal of difficult upper urinary tract calculi (1985)
    Springer
    World journal of urology 3 (1985), S. 19-23 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Percutaneous nephrolithotomy has become an established procedure for urologic surgery. For the stone which is poorly accessible or of large volume, special approaches and techniques are essential for success. For example, exact anatomical conceptualization and pinpoint puncture are vital. These requirements are aided by retrograde hyperinflation with contrast medium and C-arm fluoroscopy. Sometimes multiple percutaneous nephrostomy tracts are required or the tract must be directed so that it courses transpleurally. Among the large number of instruments available for percutaneous nephrostomy, flexible endoscopy becomes increasingly important for the difficult stone. Intrarenal electrosurgery is also important. Finally, for ureteral stones, retrograde flushing with CO2 or saline through a percutaneous sheath may be useful. These additional approaches when judiciously applied can result in a stone-free status for virtually 100% of patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326882
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Orchiectomy alone in clinical stage A disease (1984)
    Springer
    World journal of urology 2 (1984), S. 64-67 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326937
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Newer ideas about fertility in patients with testicular cancer (1984)
    Springer
    World journal of urology 2 (1984), S. 26-31 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The outlook for fertility among patients who are treated for testicular cancer is one of guarded optimism. Although some of these men are subfertile before the onset of their disease, it is probable that the majority, although temporarily subfertile because of their tumors, have a potential for normal fertility. Lymphadenectomy probably can be performed effectively while preserving ejaculation in most patients. Likewise, the effects of platinum-based chemotherapy appear to be reversible in many patients, and there is hope that spermatogenesis can be protected during chemotherapy by endocrine manipulation. During the next decade, the preservation of fertility will become an increasingly important issue in the management of testicular cancer as investigators consolidate therapeutic gains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326929
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  • 5
    Electronic Resource
    Electronic Resource
    Editorial (1984)
    Springer
    World journal of urology 2 (1984), S. 1-1 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326924
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Recent reflections on tumor markers (1984)
    Springer
    World journal of urology 2 (1984), S. 18-25 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The necessity for monitoring serum levels of alphafetoprotein (AFP) and human chorionic gonadotropin (hCG) in patients with testicular cancer is widely known, but a few questions remain unanswered. Cross-reactivity of commercial hCG assays with luteinizing hormone remains a problem; and as patients apparently cured of testicular cancer age, they become subject to other diseases that can elevated AFP or hCG levels, creating confusion. There still are no adequate studies of the role of markers in staging, a problem that has become acute with the introduction of expectant treatment for metastases in clinical stage A disease. Calculation of the metabolic half-life of markers can be helpful in staging postoperatively, but calculations of the actual half-life of markers during induction chemotherapy is less useful than had once been hoped. Attempts to capitalize on the molecular heterogeneity of AFP have had little success, although newer analytic methods may change this; but ultrasensitive assays for urinary hCG are beginning to show promise. Studies of radioimmunodetection with anti-marker antibodies have been both encouraging and frustrating; the newly available monoclonal anti-marker antibodies may improve the results and also offer a possible means of improving chemotherapy. Placental alkaline phosphatase continues to look like a useful marker for seminoma, and lactic dehydrogenase is often helpful in all types of testicular cancer, especially in high-stage disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326928
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  • 7
    Electronic Resource
    Electronic Resource
    Technical nuances of extended retroperitoneal dissection for low-stage nonseminomatous testicular germ-cell cancer (1984)
    Springer
    World journal of urology 2 (1984), S. 43-47 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Lymphadenectomy-based treatment for low-stage nonseminomatous testicular cancer is a proven therapy. The operation is difficult, but the mortality rate has been low, less than 1% in most major centers. Patients need careful psychological preparation before surgery. Patients with persistent aspermia despite limitation of the dissection distally sometimes can be treated with various sympathomimetic drug combinations. It is important to know that there is more than one way to do the operation, but the result should be the same; namely, a thorough removal of all potentially tumor-bearing tissues in the retroperitoneum. Although there is debate as to what the limits of this operation should be, we have advanced a rationale to support suprahilar dissections in most cases. Nuances in technique will determine the adequacy of exposure, the completeness of the operation, and the incidence of complications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326932
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  • 8
    Electronic Resource
    Electronic Resource
    A comparison of the two types of penile prostheses used in the surgical treatment of male impotence (1978)
    Springer
    Sexuality and disability 1 (1978), S. 307-311 
    Details
    ISSN: 1573-6717
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Psychology
    Notes: Abstract A comparison of the Small-Carrion and Scott-Bradley penile prostheses, based on our experience with their use over the last three years, is presented. Nearly all patients given either device were satisfied with the results. Selection of the type of prostheses to be used must be made on an individual basis, taking into consideration which choice will best suit the requirements of each patient. In the majority of cases, however, the patient may make the final choice himself.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01101021
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Mechanisms, Hypotheses and Questions Regarding Prostate Cancer Micrometastases to Bone (1998)
    Springer
    Cancer and metastasis reviews 17 (1998), S. 331-336 
    Details
    ISSN: 1573-7233
    Keywords: prostate cancer ; prostate specific antigen ; metastasis ; bone ; cachexia ; bone remodeling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The morbidity and mortality associated with prostate cancer can almost universally be attributed to the consequences of metastases to the bone. While clinically there have been descriptive reports of these lesions and their detection by bone scan, there is an embrrassing paucity of reports as to the mechanisms of prostate cancer cell trafficking to the bone, adaptation to the bone environment, pertubation of the normal bone reformation process and the events leading to cachexia and death. In recent years, there have been numerous in vitro studies suggesting that PSA and hK2 may play a significant biological role in these events. Also, recent data generated form reverse transcription polymerase chain reaction assays reveal that metastasis to the bone may be an early event which further underscores the need to better understand this complex and critically important process. This commentary highlights several general concepts and a few specific issues related to CaP bone metastasis with the intent of revealing numerous opportunities for further investigation and inquiry.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006106209527
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