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  • 1
    Electronic Resource
    Electronic Resource
    Sensitive detection of catalytic species without chromophoric substrates (1993)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 115 (1993), S. 2078-2080 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00058a087
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Yeastlike to mycelial phase transformation of Histoplasma capsulatum as observed by scanning electron microscopy (1971)
    Springer
    Mycopathologia 43 (1971), S. 185-193 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Details of the sequential events occurring during the critical phases of yeast to mold morphogenesis of the dimorphic fungal pathogenHistoplasma capsulatum as seen by the new technique of scanning electron microscopy are described and illustrated by electron micrographs. No conspicuous surface sculpturing was observed for the normal yeastlike cell immediately before or the newly formed hyphal cell after the critical period of transformation. However, both the parent yeastlike cell as well as the intermediate conversional cell shows a furrowing of the external cell surface which is due possibly to changes in internal cell pressure resulting from the migration of cell contents into the newly forming hyphal cell.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02051720
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Drug—induced alterations in the ultrastructural organization of Histoplasma capsulatum and Blastomyces dermatitidis (1972)
    Springer
    Mycopathologia 48 (1972), S. 289-296 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Aspects of the fine structure as seen in thin section of yeastlike cells ofHistoplasma capsulatum andBlastomyces dermatitidis exposed to polyenic antibiotics are described and illustrated by electron micrographs. The exposure of log phase yeastlike cells to minimal fungicidal concentrations of both amphotericin B (Fungizone) and hamycin resulted in detectable alterations of the plasma membrane, and, to a lesser extent, the mitochondria. WithH. capsulatum, ultrastructural changes were observed to occur within 1 h exposure to amphotericin B. Marked degenerative changes and plasmolysis were observed to occur within 6 hrs exposure of the yeastlike cells to both polyenes. The observed changes in ultrastructural appearance are compatible with the concept of binding of the polyene with membrane sterol and subsequent damage due to alterations of permeability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02052633
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Electron microscopy of the transitional conversion cell of Histoplasma capsulatum (1971)
    Springer
    Mycopathologia 44 (1971), S. 121-129 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Aspects of the fine structure of the transitional conversion cell formed during the early stages of the yeast to mold morphogenesis ofHistoplasma capsulatum as seen in ultrathin sections are described and illustrated by electron micrographs. Formation of the transitional cell was observed to occur with the highest degree of frequency between the 18th and 24th hr following induction of the conversional stimulus, although many yeastlike cells were observed to undergo degeneration or to initiate conversion only to abort the process. Cytoplasmic streaming and organelle migration from the parent yeast to the transitional cell was observed to occur prior to septation. The cell wall of the transitional form is thinner than that of the yeast and appears to arise from the inner portion of the laminated cell wall adjacent to the plasma membrane of the converting yeastlike cell. Interseptal or Woronin bodies were observed in association with the septal pore of the completed septum and were observed in the cytoplasm of both the yeastlike and transitional cell. The presence of these structures support strongly the pre-hyphal character of the converting cell complex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02051880
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  • 5
    Electronic Resource
    Electronic Resource
    Electronmicroscopy of self-parasitism by Histoplasma capsulatum and Blastomyces dermatitidis (1970)
    Springer
    Mycopathologia 40 (1970), S. 271-276 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung InHistoplasma capsulatum so wie auch inBlastomyces dermatitidis wurden in Hyphen und Zellen der Hefe- so wie auch der Mycelphase intracellular Hyphen durch Elektronmikrokopie nachgewiesen, wenn sie in flüssigen Schüttelkulturen gezüchtet worden sind. Diese Strukturen waren in Zellen der Hefephase, die zur Überleitung in die Myzelphase angeregt worden sind, sehr häufig. In vielen Fällen war eine sehr gute Bewahrung der ultrastrukturalen Einzelheiten der “parasitierten” Zelle, die es nahegelegt hat, dass die Zelle noch immer lebendig ist.
    Notes: Abstract Intrahyphal as well as intrayeast hyphae were demonstrated by electron-microscopy in bothHistoplasma capsulatum andBlastomyces dermatitidis yeastlike and mycelial phase cells grown in agitated liquid media. These structures appeared to be rather common in cultures of yeastlike cells induced to convert to the mycelial phase. In many cases there was excellent preservation of ultrastructural detail of the “parasitized” cell which suggested that the cell may still be viable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02051780
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  • 6
    Electronic Resource
    Electronic Resource
    Scanning-beam electron microscopy of the conidia of the brown and albino filamentous varieties of Histoplasma capsulatum (1973)
    Springer
    Mycopathologia 49 (1973), S. 185-191 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Aspects of the surface appearance and external morphology of the conidial forms of the albino and brown filamentous varieties ofHistoplasma capsulatum as seen by scanning-beam electron microscopy are described and illustrated by electron micrographs. Septal areas between the hyphal cells of the supporting mycelium are seen as slightly elevated annular rings or ridges. The smooth micro- and macroconidia of the albino filamentous variety show a fine wrinkling and delicate irregularities of surface texture. Macroconidia of the brown filamentous variety are illustrated showing variations in numbers and respective length of the conspicuous wall projections or tubercles. The 3-dimensional perspective, unusual depth of focus, and high resolving power of the stereoscan technique permitted observations of external conidia morphology unattainable by other methods of study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02050863
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  • 7
    Electronic Resource
    Electronic Resource
    The fine structure of the microconidium of blastomyces dermatitidis (1974)
    Springer
    Mycopathologia 52 (1974), S. 93-100 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Aspects of the fine structure of the microconidium of the mycelial phase of the dimorphic fungal pathogenBlastomyces dermatitidis as seen by techniques of scanning and transmission electron microscopy are described and illustrated by electron micrographs. The conidia ofB. dermatitidis undergo changes in the ultrastructural appearance of the cell wall as the spore matures. The cell wall becomes irregular in its thickness and possesses two distinct layers. No discrete or unique surface spines or projections were evident when the conidium ofB. dermatitidis was viewed by scanning electron microscopy. Upon maturity there is a marked deposition of lipid material in large, multiple storage bodies which occupy much of the cytoplasmic area. However, the cytoplasmic organelles appear to retain their structural integrity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02128051
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