ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
To develop osmotic granule with semi-permeable membranes, we prepared the semipermeablemembranes with different pore forming agent by using solvent casting method. Themembrane was consisted of cellulose acetate, Eudragit® RS, hydroxypropylcellulose (HPC), andtriethylcitrate (TEC) in the presence of PEG200, PEG1, 000, or dibutylsebacate(DBS) as a poreforming agent. The produced membranes were white and elastic and exhibited soft property ontouch. The release amount of pore forming agent from membrane with different pore forming agentwas measured in water dissolution media and the order was PEG200 〉 PEG1, 000 〉 DBS. Theformation of pore in membrane was observed by morphological SEM image after dissolution. Thepore formation and porosity of membrane depended on water solubility of pore forming agent. Weconfirmed that pores in porous semi-permeable membrane could be controlled by the pore formingagent
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.485.pdf
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