ISSN:
1546-1718
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Medicine
Notes:
[Auszug] The strategy to target the murine gene encoding fibrillin-1 (Fbnl) was designed to replicate the dominant-negative effect of fibrillin-1 mutations in MFS2. Because interstitial in-frame deletions account for approximately 10% of MFS mutations2, we replaced 6 kb of Fbnl encompassing exons ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/ng1097-218
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