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  • 1
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: We previously reported that dehydroevodiamine·HCl (DHED) has anticholinesterase and antiamnesic activities. To verify the effects of DHED on cognitive deficits further, we tested it on the scopolamine-induced amnesia model of the rat using the passive avoidance and eight-arm radial maze tests. A single (20 mg/kg p.o.) and repeated (10 mg/kg p.o.) administrations of DHED could significantly reverse the latency time shortened by scopolamine (1 mg/kg i.p.) to control level. The impaired spatial working memory induced by scopolamine (1 mg/kg i.p.) was also improved significantly by a single injection (6.25 mg/kg i.p.) and repeated administrations of DHED (10 mg/kg p.o.) in the eight-arm radial maze test. In addition, we examined the effects of DHED on the memory impairment and the histological changes of the brain after unilateral electrolytic lesion of the entorhinal cortex (EC) and middle cerebral artery occlusion in rats. The cognitive deficits caused by EC lesion and middle cerebral artery occlusion were improved significantly by repeated administrations of DHED (6.25 mg/kg i.p.) after EC lesion or ischemic insult once a day for 7 days in the passive avoidance test. Histological analysis showed that the neuronal loss in the DHED-treated group was notably reduced in the hippocampal area (CA1) of ischemic rats and in the dentate gyrus and hippocampal area (CA1 and CA3) of EC-lesioned rats compared with the nontreated group. The infarction area was decreased significantly by a single administration of DHED (6.25 mg/kg i.p.) 30 min before ischemic insult for 6 h. These results suggest that DHED might be an effective drug for not only the Alzheimer’s disease type, but also the vascular type of dementia.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 449-452 (Mar. 2004), p. 217-220 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Activated carbon fibers were prepared from stabilized PAN-based fibers by chemical activation using potassium hydroxide at different concentration. The experimental data showed variations in specific surface area, microstructure by the activated carbon fibers. Specific surface area of about 2545 m2/g was obtained in the KOH/stabilized PAN-based fiber ratio of 1:1 at 800°. An abrupt reduction of specific surface area was observed in the experiments with the ratio of 3:1 of OH/stabilized PAN-based fiber, being dissimilar with the result of KOH/fiber ratios of 1:1 and 2:1 in the similar experiments. The high concentration of KOH led to the destruction of micropore walls instead of forming mesopores
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 261-263 (Apr. 2004), p. 1575-1580 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this paper, presented are design, analysis, and experimental result of a tunable surface micromachined resonant accelerometer, ACRC-RXL. Also fabrication process of mechanical structure is illustrated. We used 40[μm] thick epitaxially grown polysilicon as structural layer and sealing area. With the exception of the CMP process, for smoothing the bonding area, the fabrication processes are simple as the conventional surface micromachining process. Experimental results show that the developed accelerometer has a performance of bias stability about 0.5mg and dynamic range over 10g
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 261-263 (Apr. 2004), p. 495-500 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper presents a design and performance tests of in-plane gimbal-structured Z-axis gyroscope. The device is manufactured by conventional surface micro machining process using 15µm-thickness epitaxially grown polysilicon. The total size of the device is 4.8mm x 4.8mm in area including 1mm x 1mm core gyro structure and pads for wire bonding. It is designed as two-gimbaled structure which separates inner and outer gimbals. This leads two nearly identical modes of gyroscope, i.e. driving and sensing mode, to mechanically decoupled ones, resulting in enhancedperformance. Experiments are accomplished through frequency analysis and dynamic tests using a detection circuit, a vacuum chamber and a rate table. Through experiments, it is confirmed that the designed gyroscope has 0.003 deg/sec resolution, 0.00095 deg/sec/ Hz noise equivalent density, 0.57 % FSO nonlinearity error and 0.02 deg/sec bias stability
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 326-328 (Dec. 2006), p. 1439-1442 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The efficiency of fish swimming dynamics has motivated researchers to develop fish-likerobots. As a beginning step, a fish-like robot (boat) is built to simulate the fish swimming dynamics.By using data collected from inertial sensors, a suitable mathematical model explaining fish turningdynamics is obtained through system identification method. The identified model matches well withthe experimental results and thus can be used for the design of controllers
    Type of Medium: Electronic Resource
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