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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 137 (1960), S. 45-55 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 140 (1961), S. 359-366 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The morphology of the boundary tissue of the seminiferous tubule of the rat has been investigated in testes from animals aged from birth to four months. In the adult, the boundary tissue consists of four layers: (1) an inner non-cellular layer comprising a network of collagen fibrils sandwiched between two basement membranes (2) an inner cellular layer of flattened cells showing many of the characteristics of smooth muscle, including intracytoplasmic filaments and micropinocytotic vesicles, (3) an outer non-cellular layer containing scattered colagen fibrils and associated usually with a single basement membrane and (4) an outer cellular layer, component cells of which contain no fine filaments. At birth, the seminiferous tubule rests upon a basement membrane which separates it from a layer of low cuboidal cells. External to this, there is a narrow intercellular zone containing scattered fibrillar material and a region consisting of numerous processes of mesenchyme cells. By ten days postnatal, four definite layers are established due to the differentiation of an outer cellular layer of flattened cells from the mesenchyme, and intracytoplasmic filaments have made their appearance within the inner cellular layer. In subsequent stages there is progressive thinning and specialization of the cellular layers and increased fibril content within the non-cellular layers. By 22 days postnatal the boundary tissue appears virtually adult in morphology.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 159 (1967), S. 409-419 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The fine structure of the duodenal glands of Brunner in the rabbit has been examined. The glands, which are concentrated within the submucosa, are composed of tubules that open into the bases of the intestinal glands. Unlike most species, in the rabbit two distinct cell types are present within the tubules. Serous cells, which occur in small groups in the blind endings to the tubules, contain a concentration of ergastoplasm in the basal cytoplasm and the apical cytoplasm is occupied principally by discrete secretory droplets. Intercellular secretory canaliculi occur between opposed serous cells and between serous and mucous cells. The latter cells possess little ergastoplasm but exhibit an extensive development of the Golgi apparatus in the supranuclear region. Secretory droplets are pale and show a tendency to fuse into complexes. No intercellular canaliculi occur between mucous cells.The cytological features are discussed in relation to previous observations on duodenal glands of other species, where only mucous cells are present. It is apparent that there are species differences with regard to mucous cells. These structural differences may reflect physiological and biochemical differences in the glands. The significance of the presence of serous cells in rabbit duodenal glands is unknown.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 176 (1973), S. 475-487 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A large gland patch is found in the submucosa of the lesser curvature of the koala stomach near the entrance of the esophagus. It measures approximately 3 cm in diameter and is comprised of numerous invaginations continuous with the surrounding mucosa. The glandular invaginations drain into the lumen of the stomach by 25 to 30 large orifices. The mucosa of the gland patch invaginations differs from the mucosal lining of the stomach chiefly in thickness. The elongate gastric glands that comprise the invaginations exhibit an increased number of parietal and chief cells. Ultrastructural examination of the gland patch illustrates that the parietal, chief, and mucous neck cells are similar in structure to those of other mammalian species.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 156 (1966), S. 253-267 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The appearance of Brunner's glands in the rat, before and after feeding, has been examined with the electron microscope. The glands are arranged in the duodenal submucosa in aggregates of coiled tubules which open into the bases of the crypts of Lieberkühn. Component cells appear to be more mucous than serous. The basal cytoplasm contains some granular endoplasmic reticulum, numerous free ribosomes and mitochondria. Multiple Golgi elements lie in relation to the nucleus and the apical cytoplasm contains varying concentrations of pale secretory droplets which show a tendency to fuse into complexes. Scattered between the large secretory droplets are numerous small vesicles, also considered to contain a secretory product.The cytological features are discussed in relation to previous observations on Brunner's glands in other species. It is apparent that there are considerable species differences. However, in all species it appears likely that the complex secretory materials are elaborated principally by the ergastoplasm.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 126 (1969), S. 255-273 
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The duodenal glands of the adult opossum form a lobed, glandular collar in the submucosa immediately distal to the pyloric sphincter. They empty into funnel-shaped mucosal depressions. The depressions, which form two or three irregular rows that run parallel to the pyloroduodenal junction, are lined by either pyloric or intestinal epithelium. An individual gland of Brunner has an extensive intralobular duct system which terminates in a single excretory duct just prior to entry into a depression. Histochemical studies indicate that the duodenal glands elaborate a neutral glycoprotein whereas the duct system appears to produce both neutral and acidic elements. Light and electron microscopic studies have shown the duodenal glands to consist of large, pyramidal cells which lie on a distinct basal lamina. Discrete, mottled or pale secretory granules are found in close association both with the apices of the cells and with the Golgi complexes. The ergastoplasm, cisternae of which are dilated and contain amorphous material, is associated with polysomes and, in the supranuclear region, often becomes markedly dilated, forming what appear to be large vacuoles containing fibrillar material. Blebbing of the ergastoplasm results in the formation of several small vesicles, many of which lie in close association with the Golgi network. Direct membrane continuity has been noted between the two elements.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 132 (1971), S. 133-145 
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Light and electron microscopy were combined with the technique of freeze-etch to study myoepithelial cells. Myoepithelial cells of the rat exorbital lacrimal and parotid glands are found in relation both to secretory units and intercalated ducts. They lie within the basal laminae of secretory acini and intercalated ducts and do not protrude from the external surface. The myoepithelial cell consists of a central nucleus and surrounding cytoplasm with several cytoplasmic arms, the arms being less numerous in those cells associated with the ducts. The cytoplasm is filled with fine fibrils in parallel array. The interrelationship between myoepithelial cells and acinar or ductal cells is described with the aid of frozen-etched replicas and the nature of the membrane surfaces is discussed. It is concluded that myoepithelial cells are contractile; their resemblance to smooth muscle is noted.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 126 (1969), S. 275-289 
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The postnatal development of Brunner's glands in the opossum has been traced, using 170 specimens divided into 21 groups according to snout-rump length. The newborn opossum has a well developed small intestine, possessing villi and a differentiated intestinal epithelium with concentrations of PAS-positive material in the apical cytoplasm. The ducts of the glands begin to develop within 24 hours after birth and, as they proliferate, two cell types appear. A tall, columnar cell type lines the excretory duct whereas the intralobular duct system is lined by pyramidal cells. Intralobular ducts undergo differentiation by the 50 mm stage and, after this event, secretory units appear as outgrowths from the intralobular duct system. Development continues into early adulthood.Duodenal glands appear to evaginate simultaneously at localized foci, resulting in the formation of a duodenal sinus between glandular elements. The glands evaginate from the mucosa in the most proximal portion of the duodenum, involving both intestinal and gastric mucosal elements. That portion of mucosa lying between the forming glands is submerged and forms the floor of the duodenal sinus. Excretory duct epithelium often lines the sinus in part. The development of Brunner's glands in the opossum is completely independent both of pyloric and intestinal glands.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The postnatal development of the respiratory system in the opossum has been traced, using 102 specimens divided into 11 groups according to snout-rump length. At birth, the lung is markedly underdeveloped and is represented by a pumitive system of branching airways that end in a number of terminal chambers or sacs. The airways, constituting the conducting portion of the lung, are lined by columnar epithelium that is devoid of cilia and goblet cells. The terminal air chambers contain an extensive capillary bed and are surfaced by squamous epithelium interspersed with scattered cuboidal cells. By the 3 cm stage, bands of smooth muscle have differentiated in relation to the bronchial epithelium and scattered cilia are present in the epithelium of the trachea and bronchi. Air chambers immediately adjecent to established bronchi differentiate further and become incorporated into the bronchial tree and new air chambers develop at the most distal extent of the bronchial system up to the 15.5 cm stage. Numerous spaces lined by squamous epithelium, which represent the first appearance of the arbor alveolaris, appear within the cellular stroma of the lung of the 7 cm opossum. By the 20 cm (juvenile) stage, mature alveoli, containing many vacuolated cells, are present and a thick collagenous lamina has developed between the pleura and the lung parenchyma.
    Type of Medium: Electronic Resource
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