ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The mass spectrometric behaviour of the 1,3-diaminopropane derivative 4a (3,7-diacetyl-3,7-diazadodecane) was investigated with regard to the fragmentation reactions of N, N′, N″-triacetylspermidine (1), as model for the 1,3-diaminopropane part. It was established that the degradation reactions in 4a and 1 are essentially the same and mainly due to the interaction of two N-acetyl groups. Thereby it is established that the most important mass spectrometric fragmentation reactions of spermidine derivatives take place within the 1,3-diaminopropane unit and are independent of the influence of further N-atoms in the molecule. An ion (m/e 143) was found in the fragmentation pattern of N, N′, N″-triacetylspermidine whose formation can be explained by interaction of all three N-acetyl groups. The corresponding ion was not found, in the spectrum of 4a, with only two N-acetyl groups, thereby confirming the earlier hypothesis.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19720550604
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