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  • 1
    Electronic Resource
    Electronic Resource
    T-lymphocyte activation in IgA nephropathy: Serum-soluble interleukin 2 receptor level, interleukin 2 production, and interleukin 2 receptor expression by cultured lymphocytes (1989)
    Springer
    Journal of clinical immunology 9 (1989), S. 485-492 
    Details
    ISSN: 1573-2592
    Keywords: IgA nephropathy ; lymphocyte ; cellular and soluble interleukin 2 receptor ; interleukin 2
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The present study was undertaken to examine the T-lymphocyte activation in IgA nephropathy. Serum-soluble interleukin 2 receptor (sIL2R) levels were studied in 29 IgA nephritic patients, 17 patients with chronic glomerulonephritis (non-IgA nephropathy), and 30 healthy controls during an infection-free period. No difference in serum sIL2R level was demonstrated among these three groups of subjects. However, the serum sIL2R levels of IgA nephritic patient rose significantly during clinical exacerbation with synpharyngitic macroscopic hematuria and the serum sIL2R levels fell when hematuria subsided. Mitogen-stimulated cellular interleukin 2 receptor (IL2R) expression, sIL2R release, and interleukin 2 (IL2) production were also examined in peripheral blood mononuclear cells (PBMC) cultured for 24–48 hr in 21 patients with IgA nephropathy, 17 patients with chronic glomerulonephritides, and 17 healthy controls. The total cellular IL2R expression and sIL2R release did not differ among these three groups of subjects. However, the individual T-cell subsets bearing IL2R were distinctly different between IgA nephritic patients and the other two groups of controls. IgA nephritic patients had increased activated CD4+ lymphocytes and reduced activated CD8+ lymphocytes. Furthermore, IL2 production in response to phytohemagglutinin and pokeweed mitogen stimulation was increased in lymphocytes from patients with IgA nephropathy. The IL2 production did not correlate with the quantities of cellular and sIL2R yet the cellular IL2R expression paralleled the sIL2R released by cultured lymphocytes. Our present study suggests that the T lymphocytes from patients with IgA nephropathy have a defect in overproduction of IL2 and increased activated T helper-cell subset upon mitogenic stimulation. Serum measurement of sIL2R could potentially be useful in monitoring the disease activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00918018
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Anti-neutrophil cytoplasmic antibodies (ANCA) and inflammatory bowel diseases in Chinese (1994)
    Springer
    Digestive diseases and sciences 39 (1994), S. 886-892 
    Details
    ISSN: 1573-2568
    Keywords: antineutrophil cytoplasmic antibodies ; inflammatory bowel disease ; Chinese
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Inflammatory bowel diseases are uncommon in the Chinese, but the incidence is rising. Their differentiation from infective colitis is often not clear-cut and diagnosing inflammatory bowel diseases can be difficult in Asia. We have studied Chinese patients with ulcerative colitis (N=19) and Crohn's disease (N=12) for anti-neutrophil cytoplasmic antibodies (ANCA) by indirect immunofluorescence (IIF) and enzyme-linked immunosorbent assays (ELISA). Patients with enteric fever (N=29) and irritable bowel syndrome (N=24) were recruited as controls. Seventy-three percent of ulcerative colitis patients exhibited either p-ANCA (31%) or c-ANCA (42%) by IIF. Twenty-five percent of Crohn's disease patients were found to be p-ANCA positive. However, these ANCA were nonreactive to anti-α granule, antiproteinase 3, antimyeloperoxidase, or antilactoferrin. All positive patients had extensive colitis. Sera collected from patients suffering from enteric fever and irritable bowel syndrome were negative for ANCA by IIF and ELISA. We concluded that the detection of ANCA is helpful in diagnosing inflammatory bowel diseases. Further attempts to characterize these autoantibodies are needed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02087438
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  • 3
    Electronic Resource
    Electronic Resource
    Similarity between flashing and nonflashing two-phase flows (1990)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 36 (1990), S. 797-800 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690360520
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  • 4
    Electronic Resource
    Electronic Resource
    Venting of runaway reactions with gas generation (1992)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 38 (1992), S. 723-732 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Pressure relief venting of a runway reaction with gas generation is examined in terms of the overall system response and the associated venting requirement. This article presents an exact formulation as well as an approximate analytical approach. The latter is shown to be particularly useful in vent-sizing applications. Using an aqueous hydrogen peroxide decomposition example, the analytical results are demonstrated to agree well with the exact numerical results over a wide range of overpressure. In addition, the analytical result is shown to reduce to the correct limit for a pure vapor system and offers a useful vent-sizing equation for a pure-gassy system.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690380509
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  • 5
    Electronic Resource
    Electronic Resource
    Pressure relief consideration for refrigeration equipment (1996)
    New York, NY [u.a.] : Wiley-Blackwell
    Process Safety Progress 15 (1996), S. 66-73 
    Details
    ISSN: 1066-8527
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Pressure relief sizing for refrigeration equipment is considered in this paper. In particular the ASHRAE fire sizing formula [2] is critically examined and comparisons are made with methods employed in other engineering institutes. The traditional sizing approach based on vapor relief is re-exmained in light of the recent findings from the DIERS (Design Institute for Emergency Relief Systems) work [11]. The occurrence of two-phase discharges during relief may result in significant overpresurization of the refrigeration equipment. The purpose of this paper is to suggest a methodology adequate for most designs and which has been verified with available experimental data.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prs.680150204
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  • 6
    Electronic Resource
    Electronic Resource
    Emergency relief vent sizing for fire emergencies involving liquid-filled atmospheric storage vessels (1986)
    New York, NY : Wiley-Blackwell
    Plant/Operations Progress 5 (1986), S. 205-208 
    Details
    ISSN: 0278-4513
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: For large atmospheric vessels the potential occurrence of sufficient liquid swell resulting in two-phase flow is of special importance. Based upon an extension of analytical work it would appear justifiable to ignore two-phase flow effects for non-foamy systems.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prsb.720050406
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  • 7
    Electronic Resource
    Electronic Resource
    Runaway system characterization and vent sizing based on diers methodology (1987)
    New York, NY : Wiley-Blackwell
    Plant/Operations Progress 6 (1987), S. 77-83 
    Details
    ISSN: 0278-4513
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This article reveals the diverse nature of runaway systems as well as some general trends. In addition, it also serves to point out the usefulness of such an apparatus in characterizing virtually unknown systems.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prsb.720060208
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    Paper (German National Licenses)
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