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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    FEBS Letters 115 (1980), S. 319-324 
    ISSN: 0014-5793
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0014-5793
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0014-5793
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 87 (1987), S. 517-529 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In order to monitor changes in the apical cell membrane of rabbit uterine epithelium which are postulated to be a precondition for trophoblast attachment, the marker enzymes: alkaline phosphatase, aminopeptidase M, γ-glutamyl transferase and dipeptidyl peptidase IV were investigated during the periimplantation phase. Endometrium of early pregnancy (implantation chamber, interblastocyst endometrium; 5–8 days post coitum, d p.c.) was compared with specimens obtained at hCG-induced pseudopregnancy (p. hCG) to distinguish between membrane changes regulated by maternal plasma steroid hormones and such which might be induced locally by blastocyst-derived signals. All enzymes tested showed their main activity at 5 d p.c./p. hCG. The weakest reaction in this series of stages was generally found at 8 d p.c. (interblastocyst segments) or at 8 d p. hCG. In contrast to the rest of the epithelium, the implantation chamber retained high activity of dipeptidyl peptidase IV, and the activity of alkaline phosphatase even raised here again at 7 and 8 d p.c. indicating a direct local influence of the blastocyst on the luminal epithelium. The results suggest that 1) considerable changes occur in the composition of the apical plasma membrane of the uterine epithelium when the endometrium enters the “receptive state”, 2) the overall trend is towards a loss of apical-type characteristics of this membrane domain and 3) the changes are modulated both systemically (by plasma steroid hormone levels) and locally by signals from the implanting blastocyst.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 95 (1991), S. 449-458 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Tenascin is a large glycoprotein of the extracellular matrix. Previous reports have demonstrated that it is associated with epithelial-mesenchymal interfaces and is expressed during embryonic and tumour development, wound healing, cell proliferation and it may be involved in immunomodulation. The human placenta shows numerous features related to these aspects. We have investigated the presence of tenascin in the human placenta throughout pregnancy by immunohistochemistry. We used monoclonal (mAb) and polyclonal (pAb) antibodies to tenascin, a mAb to fibrin, a pAb to fibrinogen, and the mAb Ki-67 as proliferation marker. Tenascin was highly expressed in the mesenchymal villi which are considered the basis of growth and differentiation of the villous trees. Moreover, fibrinoid deposits at the surfaces of the villous trees were always separated from the fetal stroma by tenascin. The stroma of villi encased in fibrinoid was also positive for tenascin. This glycoprotein was also expressed in the villous stroma directly apposed to cell islands and cell columns. In the proximal portions of both epithelial structures, cytotrophoblast was Ki-67 positive. These data show that tenascin is expressed during the development of the placenta, particularly in the mesenchymal villi, cell islands and cell columns. These structures are considered to be the proliferating units of the villous trees. Tenascin underlying fibrinoid deposits suggests that it also participates in repair mechanisms. Thus, in the human placenta tenascin expression can be correlated with villous growth, cell proliferation, and fibrinoid deposition. Its role in immunoprotection of fetal tissues in areas where syncytiotrophoblast as barrier is missing or damaged is discussed.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European biophysics journal 7 (1981), S. 335-337 
    ISSN: 1432-1017
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0878
    Keywords: Key words: Endometrium ; Epithelial cells ; Cell culture ; Polarization ; Steroid hormones ; Hormone receptors ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Uterine epithelial cells from normal human endometrium were cultured as a primary cell culture in a dual-chambered system. The epithelial cells were isolated from endometrial tissue of the proliferative phase obtained by hysterectomy. The epithelial cells were seeded on Millicell CM filters coated with the extracellular matrix Matrigel. Depending on the culture conditions, the epithelial cells formed a polarized cell monolayer on Matrigel or gland-like structures in Matrigel. The epithelial cell polarity was maintained during culture, which could be proved by electron microscopy. The progesterone and estrogen receptors as typical marker molecules for physiologically intact endometrial epithelial cells could be detected immunohistochemically as well as by RT-PCR in vitro and were down-regulated by medroxyprogesterone acetate (MPA) used as progesterone analogue. As this cell culture system exhibits morphological and immunohistochemical characteristics, typical for the in vivo situation, and since it can be modulated by hormone treatment under the in vitro conditions described, it represents a valuable tool for investigating processes that are essential for endometrial differentiation and reproductive functions.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 415 (1975), S. 156-160 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Investigations on Electronically Conducting Oxide Systems. I. Glass Formation in the System K2O—SiO2—VO2Glass formation in the system K2O-SiO2-VO2 was investigated. The glass forming region is compared with the glass formation in the system K2O-SiO2-TiO2. Density and electrical conductivity of the glasses are discussed in denpendence on the composition.
    Notes: Es wird über Gläser im System K2O—SiO2—VO2 berichtet. Der Glasbildungsbereich wird mit der im System K2O—SiO2—TiO2 auftretenden Glasbildung verglichen. Dichte und elektrische Leitfähigkeit der Gläser werden in Abhängigkeit von der Zusammensetzung diskutiert.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 437 (1977), S. 237-244 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Glass Formation and Properties of Chalcogenide Systems. XI. Relations between Structure and Properties in Ge—Sn—Se—Te GlassesStarting from the glass formation range Ge—Sn—Se—Te the mutual influence of the in couples homologous elements on molar volume, glass transition temperature and electrical conductivity of glasses is studied in the series Ge0.4-xSnxSe0.6-yTey. MÖSSBAUER spectra show the presence of SnII atoms in the whole range. The course of properties suggests a modifier function of SnSe and SnTe in the glass structure which is based on a network of [GenX(2n+2)/2] subgroups (X = Se, Te).
    Notes: Ausgehend von Glasbildungsbereich wird der wechselseitige Einfluß der paarweise homologen Elemente auf Molvolumen, Transformationstemperatur und elektrische Leitfähigkeit der Gläser in der Reihe Ge0,4-xSnxSe0,6-yTey untersucht. Mössbauer-Spektren belegen das Vorliegen von SnII-Atomen im gesamten Glasbildungsbereich. Der Verlauf der Eigenschaften läßt auf eine Netzwerkwandler-Funktion von SnSe bzw. SnTe im Strukturgerüst der Gläser schließen, dem ein Aufbau aus [GenX(2n+2)/2]-Baugruppen (X = Se, Te) zugrunde gelegt wird.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 415 (1975), S. 161-168 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Investigations on electronically Conducting Oxide Systems. II. On the Transition from Ionic to Electronic Conductivity of Glasses in the Series (BaO)x(K2O)25-x(SiO2)50-(VO2)25Glass formation and properties in the system (BaO)x(K2O)25-x(SiO2) 50(VO2)25 are described. Glasses containing TiO2 for VO2 are used for comparison. When the substitution of BaO for K2O is arising the glass transition temperature and density is increasing. In every case, the density of the TiO2 -containing glasses is a little higher than that of the corresponding samples of the VO2-series. For the glass transition temperature this relation is reversed. The ionic conductivity is drastically reduced when BaO is substituted stepwise for K2O, but in the beginning the values agree for corresponding samples of the two series. On the other hand, the conductivity of the VO2-containing glasses increases for x ≥ 12.5 mole-% by two orders of magnitude, whereas the activation energy decreases. This behaviour is discussed in relation to the polaron theory.
    Notes: Es wird über Glasbildung und Eigenschaften in der Reihe (BaO)x(K2O)25-x(SiO2)50(VO2)25 berichtet. Dabei werden Gläser, die TiO2 anstelle von VO2 enthalten, als Vergleichssubstanzen verwendet. Transformationstemperatur und Dichte nehmen mit wachsender Substitution von K2O durch BaO zu, wobei die TiO2 enthaltenden Gläser die größere Dichte und eine gegenüber den Gläsern der VO2-Reihe geringfügig erhöhte Transformationstemperatur aufweisen. Die Ionenleitfähigkeit stimmt für beide Reihen anfangs überein und fällt mit zunehmender Substitution bei den TiO2 enthaltenden Gläsern auf extrem kleine Werte ab. Demgegenüber tritt bei den Gläsern der VO2-Reihe ab x ≥ 12,5 Mol-% Elektronenleitfähigkeit auf, die im Verlauf der weiteren Substitution von K2O durch BaO bei gleichzeitiger Abnahme der Aktivierungsenergie um 2 Größenordnungen anwächst. Die Änderung der Polarisierbarkeit der Sauerstoffionen und der daraus resultierende Einfluß auf den Polaronenzustand der Ladungsträger wird hierfür als Ursache angesehen.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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