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  • 1
    Electronic Resource
    Electronic Resource
    MEDICAL APPLICATION OF THE VELOUR FABRICS (1968)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 146 (1968), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1968.tb20290.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    124. Mechanische orthotope Substitution des Herzens:In vitro-Untersuchungen kardialer Prothesen (1971)
    Springer
    Langenbeck's archives of surgery 329 (1971), S. 375-383 
    Details
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In einem eigens entwickelten Kreislaufsimulator wurden in den letzten Jahren drei verschiedene Typen pneumatisch betriebener künstlicher Ventrikel auf ihre Leistungsfähigkeit ausgetestet. Mit einem maximalen effektiven Minutenvolumen von 60% des vorberechneten Wertes erwiesen sich der ursprüngliche unidiaphragmale Typ und eine bidiaphragmale Neukonstruktion einer sackförmigen Konstruktion überlegen. Maßgebend für die Effektivität eines künstlichen Ventrikels ist neben der Beschaffenheit der Außenschale und der Form der Trennmembran zwischen pneumatischem und hämodynamischem bzw.hydrodynamischem System des Klappenmechanismus. Daher wurden die hydrodynamischen Eigenschaften verschiedener Klappen im Zusammenhang mit dem bidiaphragmalen Ventrikel untersucht. Um das Schlagvolumen optimal zu halten, muß die InfloWoder Mitralklappe einen möglichst kleinen Gradienten aufweisen, während bei der Outflow- oder Aortenklappe eine möglichst geringgradige Insuffizienz gefordert wird. Von den getesteten Klappen erfüllen in mitraler Position die montierte Fascia lata-Klappe und in aortaler Position die Björk-Shiley-Prothese diese Bedingungen am besten. Mittels sorgfältiger in vitro-Untersuchungen künstlicher Ventrikel gelingt es, gültige Aussagen über deren Leistungsfähigkeit in späteren Tierversuchen zu machen und untaugliche Modelle von vorneherein auszuschließen.
    Notes: Summary During the past years three different types of pneumatically driven artificial ventricles have been studied in a special mock circulatory system. The original unidiaphragmatic type and a bidiaphragmatic new construction yielded a cardiac output of 60% of the precalculated value. Both types were superior to a sacciform ventricle. The efficiency of an artificial ventricle is dependent upon the construction of the external wall and the form of the diaphragms separating the pneumatic and hymodynamic systems. Moreover the valve mechanism plays an important role. Therefore the hydrodynamic characteristics of different valves were studied using the bidiaphragmatic type ventricle. To guarantee an optimal stroke volume a minimal gradient across the inflow or mitral valve is mandatory while the important factor at the outflow or aortic valve is minimal backflow. Of the studied valves the stented fascia lata meets best the requirements in mitral position, while in aortic position the Björk-Shiley tilting disc prosthesis gives the best results. The efficiency of a new artificial ventricle can be tested by careful in vitro studies in a mock circulatory system and it is possible to eliminate a unfit type before expensive animal experiments are started.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01770543
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  • 3
    Electronic Resource
    Electronic Resource
    Velour fabrics applied to medicine (1967)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 1 (1967), S. 179-196 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Warp-knitted velour fabrics of Dacron, nylon, polypropylene, and Rayon have been backed with Silastic to form a laminate. Prior to heat curing, the composite can be molded into many shapes and has been successfully used to line the luminal side of blood pumps and vascular grafts. Prosthetic heart valves are being covered with velour in an attempt to promote a more compatible surface. Velour suture rings are being evaluated as a more efficient anchor for prosthetic heart valves. Silastic tubes with velour bonded to the outer wall have been used to inhibit infection and sinus tract formation where percutaneous lead wires and conduits are necessary. As a flat sheet, the Silastic-velour laminate has been used experimentally as an artificial skin, but the most noteworthy experimental results have been obtained in rats using a double layer of nylon velour, separated by an impermeable layer of poly(vinyl fluoride). Future application will include attempts to anchor artificial limbs via a velour interface and made functional by tendinous attachment.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820010202
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  • 4
    Electronic Resource
    Electronic Resource
    Implantation of autologous tissue fragments in velour fabric used to line cardiovascular prostheses: An in vivo culture system to produce cellular blood-prosthesis interfaces (1968)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 2 (1968), S. 201-208 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Previous observations of pseudointimal organization within impermeable cardiovascular prostheses indicated that rapid spontaneous healing was dependent upon proximity of host vascular tissue at the suture line. Autologous connective tissue fragments were prepared from skeletal muscle biopsies by blender-mincing muscle tissue. The fragments were embedded in the fabric used to line the inner wall of arterial prostheses. A tightly fitting piston was drawn through the prosthesis, forcing the suspended tissue fragments to flow around the piston and become entwined in the loops of the velour fabric. The arterial prostheses prepared in this way were inserted as replacements for segments of canine abdominal aorta. This in vivo culture system supported cellular proliferation and pseudointimas healed uniformly. Pseudointimas of paracorporeal pumps in operation for as long as 5 weeks did not show signs of healing. The same principle of filtration of tissue fragments into a lining fabric was applied to diaphragms of left ventricular bypass pumps. This type of paracorporeal pump supported in vivo culture of implanted fragments.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820020203
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    Paper (German National Licenses)
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