ISSN:
1617-4623
Keywords:
Balancer chromosomes Polytene chromosomes Ceratitis capitata Diptera Tephritidae
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract. The construction of the first balancer chromosome, FiM1, for the medfly Ceratitis capitata is described. This chromosome has three overlapping pericentric inversions and is marked with dominant and recessive mutations. The inversion breakpoints of FiM1 suppress recombination throughout the length of the fifth chromosome, allowing lethal mutations to be recovered and maintained. This chromosome will provide a powerful tool for the manipulation of laboratory stocks, in particular, the recovery of new mutant and transgenic strains. We demonstrate the use of FiM1 for the recovery and maintenance of chromosomes carrying lethal mutations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004380000294
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