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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 41 (1994), S. C214 
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Chronically inflamed tissues contain significant concentrations of oxygen radicals, possibly generated by transition metal species such as Fe(II) and Cu(I). In addition, the pH of such tissues may well be lower than that of normal counterpart tissues. In this communication, the effect of variation of pH on the antioxidant activity of caeruloplasmin (a copper-containing acute-phase protein possessing important ferroxidase and other antioxidant activities) and of heparin are reported. Heparin, unlike caeruloplasmin, retains antioxidant activity at low pH. Heparins possess a variety of metal cation-binding chemical groups allowing them to bind damaging Cu(I) and Fe(II) ions and consequently prevent their redox involvement in oxygen radical-generating Fenton reactions. In conclusion, heparins may function as endogenous antioxidants and sequestration and/or oxidation by them, of ions such as Fe(II), may contribute to their effectiveness.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 116-117 (1984), S. 572-575 
    ISSN: 1573-5117
    Keywords: seaweed ; porphyran ; agarases ; 13C-NMR
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 116-117 (1984), S. 576-579 
    ISSN: 1573-5117
    Keywords: seaweed ; agarases ; Pseudomonas atlantica
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-5117
    Keywords: Corallina ; calcification ; Rhodophyta ; seaweeds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The effects of a range of fractions from calcareous and non-calcareous marine red algae on the crystal growth of calcite-seeded supersaturated calcium carbonate solutions were monitored by measuring the change in conductivity. An effective inhibitor of crystallization was a macromolecular fraction derived from the coralline red alga, Corallina officinalis, by a series of acid and alkali treatments. A preliminary characterization of the extract suggests the presence of a protein-polysaccharide complex. The possibility that this participates in the modulation of calcification in vivo is suggested.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1860-0980
    Source: Springer Online Journal Archives 1860-2000
    Topics: Psychology
    Notes: Abstract A modification of the Wherry-Doolittle test selection method is presented by which tests are included in a multiple correlation (obtained for a given battery of tests) in the sequence in which the rate of return in validity per unit of testing time is greatest, rather than in the order of the size of their contribution to the multiple correlation. It is proposed that the modified method can be utilized profitably when there are economic or practical limits on the time available for test administration.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-5176
    Keywords: Porphyra ; Rhodophyta ; cell culture ; polysaccharide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A range of cell lines was isolated fromPorphyra umbilicalis L. (Rhodophyta) tissue using a variety of methods, the most successful involving exposure to a limpet acetone powder enzyme extract for 24 h, homogenisation and filtration through a series of polyester meshes. All established lines grew as 0.1–5 mm diameter aggregates in liquid culture; most were stable and have been grown in shake-flask or air-lift culture for periods in excess of 1 yr without reverting to the foliose growth form. An investigation of the medium used to grow these lines indicated that it was not nitrogen-deficient and that the sodium chloride concentration was optimal. The addition of an organic buffer increased the final cell yield. None of these cell lines grew heterotrophically in medium supplemented with a range of fixed carbon sources. The infrared spectra of polysaccharides isolated fromPorphyra aggregates and from tissue grown under identical conditions indicated that the structures of the two isolates were analogous.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 36 (1972), S. 18-22 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Treatment of chick embryo cells with 1-adamantanamine prevented the synthesis of fowl plague virus-directed RNA and the development of the virusinduced depression of cellular protein synthesis. The event sensitive to the compound preceded an early event sensitive to cycloheximide. Interferon production induced by ultraviolt-irradiated virus was depressed by the compound. These data suggest that 1-adamantanamine prevents the release of viral nucleic acid within the cell.
    Type of Medium: Electronic Resource
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