ISSN:
1573-8221
Schlagwort(e):
carcinogenic hydrocarbons
;
metabolites
;
fluorescence
;
hairless mice
;
skin
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Abstract The effect of two metabolites of 7,12-dimethylbenz(a)anthracene (DMBA)—7-hydroxymethyl-12-methylbenz(a)anthracene and 7,12-dihydroxymethylbenz(a)anthracene—on the dynamics of its fluorescence in the skin of living mice was studied. The first metabolite did not change the dynamics of DMBA fluorescence whereas the second, if applied to the skin in equimolar proportions with DMBA, delayed its fluorescence. A similar effect was obtained with 7,8-benzoflavone—an inhibitor of DMBA metabolism.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00842647
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