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  • 1
    Electronic Resource
    Electronic Resource
    Self-Expanding Endovascular Stent-Graft Implant for Treatment of Descending Aortic Diseases (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiac surgery 14 (1999), S. 0 
    Details
    ISSN: 1540-8191
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: AbstractBackground: Aneurysms and dissections involving the descending thoracic aorta and the distal portion of the aortic arch are difficult to resolve surgically. The introduction of endovascular self-expanding stent-grafts has simplified the operation. Given the complications associated with their peripheral placement, we explored the feasibility of surgical insertion. Methods: Thirteen patients underwent surgical insertion of a stent-graft into the aortic arch via longitudinal aortotomy. Six patients had aneurysms (ruptured in two, and seven dissections (acute in two, ruptured in one). Five patients also underwent associated procedures including aortic valve replacement (one), ascending aorta replacement (two), arch replacement (one), and coronary artery bypass (one). Results: There was one intraoperative death due to ascending aortic dissection, and two hospital deaths due to multiple complications. Of ten patients discharged, one died 3 months postoperatively. The remaining survivors are well, and imaging studies confirmed adequate correction of the aortic disease. Conclusions: The use of this technique simplifies the operation and treatment of particular cases of aortic disease. The observed morbidity and mortality are due to factors independent of the technique.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8191.1999.tb00944.x
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  • 2
    Electronic Resource
    Electronic Resource
    Randomized, double-blind clinical trial, controlled with placebo, of the toxicology of chronic melatonin treatment (2000)
    Copenhagen : Munksgaard International Publishers
    Journal of pineal research 29 (2000), S. 0 
    Details
    ISSN: 1600-079X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The objective of the present study was to assess the toxicology of melatonin (10 mg), administered for 28 days to 40 volunteers randomly assigned to groups receiving either melatonin (N=30) or placebo (N=10) in a double-blind fashion. The following measurements were performed: polysomnography (PSG), laboratory examinations, including complete blood count, urinalysis, sodium, potassium and calcium levels, total protein levels, albumin, blood glucose, triglycerides, total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL), urea, creatinine, uric acid, glutamic-oxalacetic transaminase (GOT), glutamic-pyruvate transaminase (GPT), bilirubin, alkaline phosphatase, gama-glutamic transaminase (GGT), T3, T4, TSH, LH/FSH, cortisol, and melatonin serum concentrations. In addition, the Epworth Somnolence Scale (ESS) and a sleep diary (SD) were also applied to the volunteers 1 wk before each PSG. In addition, the volunteers were asked about possible side effects (SE) that appeared during the treatment. The study was carried out according to the following timetable: Visit 0, filling out the term of consent and inclusion criteria; Visit 1, PSG, laboratory examinations, ESS, SD, melatonin serum concentrations; Visit 2, SD, melatonin serum concentrations, SE; Visit 3, melatonin serum concentrations, PSG, ESS, SE; Visit 4, laboratory examinations, SE, melatonin serum concentrations, SD; and Visit 5, PSG, ESS, SE. Analysis of the PSG showed a statistically significant reduction of stage 1 of sleep in the melatonin group. No other differences between the placebo and melatonin groups were obtained. In the present study we did not observe, according to the parameters analyzed, any toxicological effect that might compromise the use of melatonin at a dose of 10 mg for the period of time utilized in this study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0633.2002.290401.x
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  • 3
    Electronic Resource
    Electronic Resource
    Book reviews (1990)
    Springer
    Child's nervous system 6 (1990), S. 183-183 
    Details
    ISSN: 1433-0350
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00308498
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  • 4
    Electronic Resource
    Electronic Resource
    Vitamin D-binding protein in the perinatal period (1985)
    Springer
    European journal of pediatrics 144 (1985), S. 228-229 
    Details
    ISSN: 1432-1076
    Keywords: Vitamin D-binding protein ; Polymorphism ; Quantitative data ; Newborn infant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The molecular polymorphism and quantiative levels of serum vitamin D-binding protein (DBP) were ascertained in a group of preterm, full-term and hypocalcaemic full-term newborn infants. The serum concentration of DBP is not influenced by phenotype and increases with fetal age from the 32nd–33rd week of gestation until the 35th week of gestation. Neither different DBP allele distribution nor abnormal quantitative levels found among 29 hypocalcaemic full-term newborn infants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00451946
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  • 5
    Electronic Resource
    Electronic Resource
    Intraventricular streptokinase infusion in acute post-haemorrhagic hydrocephalus (1998)
    Springer
    Intensive care medicine 24 (1998), S. 526-529 
    Details
    ISSN: 1432-1238
    Keywords: Key words Intraventricular haemorrhage ; Post-haemorrhagic hydrocephalus ; Term infants ; Streptokinase intraventricular infusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Neonatal post-haemorrhagic hydrocephalus is a clinical condition with a high mortality and long-term morbidity. Its clinical management is difficult and not well standardized. We describe the case of a term baby suffering from acute intracranial hypertension caused by an intraventricular and thalamic haemorrhage. In this case, the external ventricular drain inserted to control intracranial pressure was ineffective because of repeated obstructions due to blood clots. Continuous intraventricular infusion of streptokinase of 20 000 U/day allowed quick lysis of the clots, drainage of the cerebrospinal fluid and relief from the coma. Although it did not prevent a permanent ventriculoperitoneal shunt, we obtained reabsorption of the intraventricular haemorrhage without rebleeding complications. We suggest the use of low-dose fibrinolytic infusion through an external drain for the treatment of acute intracranial hypertension following intraventricular haemorrhage in term infants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340050606
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  • 6
    Electronic Resource
    Electronic Resource
    Doppler evaluation of renal blood flow velocity as a predictive index of acute renal failure in perinatal asphyxia (1998)
    Springer
    European journal of pediatrics 157 (1998), S. 656-660 
    Details
    ISSN: 1432-1076
    Keywords: Key words Perinatal asphyxia ; Neonatal acute renal failure ; Doppler ultrasonography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aim of our study was to evaluate Doppler renal blood flow velocity in asphyxiated neonates and to correlate renal function to Doppler findings. Doppler renal blood flow velocity was evaluated in 23 severely asphyxiated neonates born at a gestational age 〉32 weeks and compared to our standard Doppler data obtained in 25 healthy neonates comparable for gestational age and birth weight. Renal Doppler ultrasound was performed on the 1st and 3rd days of life. Renal function was investigated in the first 2 weeks of life. Asphyxiated neonates showed mean values of systolic velocity and mean velocity significantly reduced (P〈 0.001) compared with our standard Doppler values on the 1st day of life. Seven out of the 23 asphyxiated neonates were affected by acute renal failure and 14 showed no renal involvement. Two neonates were oliguric but did not develop acute renal failure. On the 1st day of life, neonates with acute renal failure had significantly lower mean values of systolic velocity and mean velocity than the asphyxiated neonates without renal involvement (P〈 0.01). All 7 neonates affected by acute renal failure showed a systolic velocity more than 2SD below the mean standard value, while only 4 of the 16 asphyxiated neonates (25%) without acute renal failure had low systolic velocity values on the 1st day of life. Doppler velocities in asphyxiated neonates were similar to standard values on the 3rd day of life. Renal failure recovered before the 11th day of life in all cases. Conclusion Our findings indicate that decreased Doppler renal flow systolic velocity observed in asphyxiated neonates on the 1st day of life is a useful predictive index for subsequent development of acute renal failure, with 100% sensitivity and 63.6% specificity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050905
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  • 7
    Electronic Resource
    Electronic Resource
    Abstracts from the CECAM workshop on computer simulations of cellular automata (1989)
    Springer
    Journal of statistical physics 55 (1989), S. 1333-1359 
    Details
    ISSN: 1572-9613
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01041096
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  • 8
    Electronic Resource
    Electronic Resource
    Minimal path on the hierarchical diamond lattice (1991)
    Springer
    Journal of statistical physics 65 (1991), S. 183-204 
    Details
    ISSN: 1572-9613
    Keywords: Minimal path ; directed polymer ; hierarchical lattice ; percolation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We consider the minimal paths on a hierarchical diamond lattice, where bonds are assigned a random weight. Depending on the initial distribution of weights, we find all possible asymptotic scaling properties. The different cases found are the small-disorder case, the analog of Lévy's distributions with a power-law decay at-∞, and finally a limit of large disorder which can be identified as a percolation problem. The asymptotic shape of the stable distributions of weights of the minimal path are obtained, as well as their scaling properties. As a side result, we obtain the asymptotic form of the distribution of effective percolation thresholds for finite-size hierarchical lattices.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01329855
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  • 9
    Electronic Resource
    Electronic Resource
    Do the simple and 2/3 majority models belong to the same universality class?: A monte carlo approach (1991)
    Springer
    Journal of statistical physics 65 (1991), S. 387-393 
    Details
    ISSN: 1572-9613
    Keywords: Geometrical critical phenomena ; majority model ; crossover ; Monte Carlo
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We extend the majority model (introduced by Tsallis in 1982) in the sense that the required majority might be different from the simple majority. We simulate these models for typical cases which include simple and 2/3 majorities. We exhibit the average cluster size as well as the order parameter as functions ofp, the concentration of one of the two possible constituents. No crossover exists between the simple- and non-simple-majority models.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01329867
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  • 10
    Electronic Resource
    Electronic Resource
    Intraventricular hemorrhage: past, present and future, focusing on classification, pathogenesis and prevention (1999)
    Springer
    Child's nervous system 15 (1999), S. 652-661 
    Details
    ISSN: 1433-0350
    Keywords: Key words Intraventricular hemorrhage ; Preterm babies ; Post-hemorrhage hydrocephalus ; Fibrinolytic endoventricular treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The improvement in the survival rate of infants born at the limit of viability, i.e. 〈26 weeks of gestational age, raises concern about the risk of neurodevelopmental disabilities. The relevance of intraventricular hemorrhage (IVH), which is the most frequent cerebral lesion diagnosed in extremely low birth weight neonates, cannot then be underestimated. Pharmacological interventions designed to prevent the occurrence of IVH and its complications have not been entirely conclusive. The understanding of pathogenetic factors involved in the genesis of IVH is the key to planning of new strategies and meanwhile of implementing care guidelines aimed at its prevention.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003810050454
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