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  • 1
    ISSN: 1432-1084
    Keywords: International MRI ; Lasers ; Neoplasms therapy ; Local hyperthermia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Interventional magnetic resonance imaging (MRI) is a newly established field, made possible by improvements in imaging times and the development of nonferromagnetic materials. Interstitial laser therapy (ILT) is a promising new technology in which laser energy is adininistered percutaneously via optical fibers. In this study, MRI was used to image acute experimental lesions induced nv ILT. Nine experimental lesions were induced in the musculature of an adult swine using an argon laser,' with output power of 1–4 watts, and exposure times of 10–40 s. T2-weighted images were obtained immediately after laser energy administration. The animal was then sacrificed and lesions were dissected and examined histologically. On MRI, target like lesions were seen with a high intensity center surrounded by two alternating concentric rings of low and high intensity. Histologically, concentric zones of tissue disruption were present. A center cavity was surrounded by a zone of coagulative necrosis, followed by a zone of vascuolated tissue abutting normal muscle. We conclude that MRI is capable of imaging acute histological changes. Appropriate development of a scale relating MR changes to acute and long-term histologic changes will allow us to optimize 3 D control and monitoring of ILT.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cancer and metastasis reviews 7 (1988), S. 19-38 
    ISSN: 1573-7233
    Keywords: magnetic resonance imaging ; head and neck tumors ; cancer of the head and neck ; CT (computed tomography)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Magnetic resonance imaging has revolutionized the imaging of head and neck malignancies and is now rapidly replacing computed tomography as the study of choice in the majority of lesions in the head, neck, larynx, hypopharynx, oropharynx, paranasal sinuses, paranasopharynx, and skull base. CT scanning can be used in the same region; however, inflammation obtained in CT is not as clearly demonstrated and in some situations, such as malignancies of the tongue, the lesions may be missed entirely. There are still occasional difficult clinical problems when the two studies are complementary, but this situation will definitely be rare.
    Type of Medium: Electronic Resource
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